Atg8-family proteins—structural features and molecular interactions in autophagy and beyond
Autophagy is a common name for a number of catabolic processes, which keep the cellular
homeostasis by removing damaged and dysfunctional intracellular components. Impairment …
homeostasis by removing damaged and dysfunctional intracellular components. Impairment …
Enhanced sampling and free energy calculations for protein simulations
Q Liao - Progress in molecular biology and translational …, 2020 - Elsevier
Molecular dynamics simulation is a powerful computational technique to study biomolecular
systems, which complements experiments by providing insights into the structural dynamics …
systems, which complements experiments by providing insights into the structural dynamics …
Integrated NMR, fluorescence, and molecular dynamics benchmark study of protein mechanics and hydrodynamics
C Möckel, J Kubiak, O Schillinger… - The Journal of …, 2018 - ACS Publications
Understanding the function of a protein requires not only knowledge of its tertiary structure
but also an understanding of its conformational dynamics. Nuclear magnetic resonance …
but also an understanding of its conformational dynamics. Nuclear magnetic resonance …
Structure and dynamics in the ATG8 family from experimental to computational techniques
Autophagy is a conserved and essential intracellular mechanism for the removal of
damaged components. Since autophagy deregulation is linked to different kinds of …
damaged components. Since autophagy deregulation is linked to different kinds of …
The Atg8 family of proteins—modulating shape and functionality of autophagic membranes
I Abdollahzadeh, M Schwarten, T Gensch… - Frontiers in …, 2017 - frontiersin.org
Aging is a multifactorial process involving an accumulation of alterations on various
organizational levels, which finally compromises viability and limits the lifespan of …
organizational levels, which finally compromises viability and limits the lifespan of …
Unlocking the gate to GABARAPL2
JCY Chan, SM Gorski - Biologia Futura, 2022 - Springer
GABARAPL2 was initially characterized for its involvement in protein transport and
membrane fusion events, but has since gained notoriety for its role in autophagy …
membrane fusion events, but has since gained notoriety for its role in autophagy …
Atg8 family proteins, LIR/AIM motifs and other interaction modes
The Atg8 family of ubiquitin-like proteins play pivotal roles in autophagy and other processes
involving vesicle fusion and transport where the lysosome/vacuole is the end station …
involving vesicle fusion and transport where the lysosome/vacuole is the end station …
Facile synthesis of covalent probes to capture enzymatic intermediates during E1 enzyme catalysis
H An, AV Statsyuk - Chemical Communications, 2016 - pubs.rsc.org
We report a facile synthetic strategy to prepare UBL–AMP electrophilic probes that form a
covalent bond with the catalytic cysteine of cognate E1s, mimicking the tetrahedral …
covalent bond with the catalytic cysteine of cognate E1s, mimicking the tetrahedral …
Autophagy Proteins and clinical data reveal the prognosis of polycystic ovary syndrome
Y Wu, J Huang, C Liu, F Wang - BMC Pregnancy and Childbirth, 2024 - Springer
Objective We aimed to investigate the significance of autophagy proteins and their
association with clinical data on pregnancy loss in polycystic ovary syndrome (PCOS), while …
association with clinical data on pregnancy loss in polycystic ovary syndrome (PCOS), while …
Structural basis for the hyperthermostability of an archaeal enzyme induced by succinimide formation
Stability of proteins from hyperthermophiles (organisms existing under boiling water
conditions) enabled by a reduction of conformational flexibility is realized through various …
conditions) enabled by a reduction of conformational flexibility is realized through various …