[HTML][HTML] Immunotherapy for HPV associated cancer

IH Frazer, J Chandra - Papillomavirus Research, 2019 - ncbi.nlm.nih.gov
Tumour immunotherapy aims to induce or enhance tumour antigen specific immune
responses that are capable of killing tumour cells. Anogenital and oropharyngeal …

RNA-based gene targeting therapies for human papillomavirus driven cancers

AM Salinas-Montalvo, A Supramaniam, NAJ McMillan… - Cancer Letters, 2021 - Elsevier
While platinum-based chemotherapy, radiation therapy and or surgery are effective in
reducing human papillomavirus (HPV) driven cancer tumours, they have some significant …

[HTML][HTML] Loss of HPV type 16 E7 restores cGAS-STING responses in human papilloma virus-positive oropharyngeal squamous cell carcinomas cells

V Bortnik, M Wu, B Julcher, A Salinas, I Nikolic… - Journal of Microbiology …, 2021 - Elsevier
Human papilloma viruses (HPV) are the main culprit in cervical and oropharyngeal cancers.
HPV positive (+) cancers are regarded as 'oncogene addicted', displaying an absolute …

[HTML][HTML] HPV16 E7-driven epithelial hyperplasia promotes impaired antigen presentation and regulatory T-cell development

AA Bashaw, SM Teoh, ZK Tuong, GR Leggatt… - Journal of Investigative …, 2019 - Elsevier
Human papillomaviruses infect keratinocytes and can lead to hyperproliferative dysplasia
and malignant transformation if not cleared by the immune system. Human papillomavirus …

[HTML][HTML] Regulatory T cells but not IL-10 Impair cell-mediated immunity in human papillomavirus E7+ hyperplastic epithelium

AA Bashaw, C Zhou, M Yu, L Tolley, GR Leggatt… - Journal of Investigative …, 2021 - Elsevier
High-risk human papillomavirus infection can induce cervical and other intraepithelial
neoplasia and invasive cancers. A transgenic mouse expressing keratin 14 promotor-driven …

[CITACE][C] Modulation of immune responses by HPV-induced epithelial hyperplasia

A Bashaw - 2020 - espace.library.uq.edu.au
Amongst the 20% of human cancers initiated by infection, those associated with infection
with human papillomaviruses (HPVs) are the most common, comprising 5% of the global …