Capillary Electrophoresis–Mass Spectrometry for Top-Down Proteomics
Mass spectrometry (MS)-based top-down proteomics (TDP) characterizes proteoforms in
cells, tissues, and biological fluids (eg, human plasma) to better our understanding of protein …
cells, tissues, and biological fluids (eg, human plasma) to better our understanding of protein …
Native Proteomics by Capillary Zone Electrophoresis‐Mass Spectrometry
Native proteomics measures endogenous proteoforms and protein complexes under a near
physiological condition using native mass spectrometry (nMS) coupled with liquid‐phase …
physiological condition using native mass spectrometry (nMS) coupled with liquid‐phase …
Top-Down Proteomics Analysis of Picogram-Level Complex Samples Using Spray-Capillary-Based Capillary Electrophoresis–Mass Spectrometry
Proteomics analysis of mass-limited samples has become increasingly important for
understanding biological systems in physiologically relevant contexts such as patient …
understanding biological systems in physiologically relevant contexts such as patient …
A simple and efficient approach for preparing cationic coating with tunable electroosmotic flow for capillary zone electrophoresis-mass spectrometry-based top-down …
Background Capillary zone electrophoresis-tandem mass spectrometry (CZE-MS/MS) has
become a valuable analytical technique in top-down proteomics (TDP). CZE-MS/MS-based …
become a valuable analytical technique in top-down proteomics (TDP). CZE-MS/MS-based …
PrSMBooster: Improving the Accuracy of Top-Down Proteoform Characterization Using Deep Learning Rescoring Models
J Zhong, C Yang, M Yuan, S Wang - International Symposium on …, 2024 - Springer
The aim of top-down mass spectrometry-based proteoform identification and
characterization is to achieve optimal alignment between mass spectra and proteoforms …
characterization is to achieve optimal alignment between mass spectra and proteoforms …
Proteoform identification using multiplexed top-down mass spectra
Top-down mass spectrometry (TDMS) is the method of choice for analyzing intact
proteoforms, as well as their post-translational modifications and sequence variations. In …
proteoforms, as well as their post-translational modifications and sequence variations. In …