The ability to explore life kingdoms is largely driven by innovations and breakthroughs in
technology, from the invention of the microscope 350 years ago to the recent emergence of …

Over the last decade, single-cell genomics has revealed remarkable heterogeneity and
plasticity of cell types in the lungs and airways. The challenge now is to understand how …

Variation in lung alveolar development is strongly linked to disease susceptibility. However,
underlying cellular and molecular mechanisms are difficult to study in humans. We have …

Harmonizing cell types across the single-cell community and assembling them into a
common framework is central to building a standardized Human Cell Atlas. Here, we present …

The rapid adoption of single-cell technologies has created an opportunity to build single-cell
'atlases' integrating diverse datasets across many laboratories. Such atlases can serve as a …

Human limbs emerge during the fourth post-conception week as mesenchymal buds, which
develop into fully formed limbs over the subsequent months. This process is orchestrated by …

The balance between self‐renewal and differentiation in human foetal lung epithelial
progenitors controls the size and function of the adult organ. Moreover, progenitor cell gene …

The lung is the primary respiratory organ in human, in which the proximal airway and the
distal alveoli are responsible for air conduction and gas exchange, respectively. However …

Studies of human lung development have focused on epithelial and mesenchymal cell types
and function, but much less is known about the develo** lung immune cells, even though …