Cancer is a major public health issue and represents the second leading cause of death in
women worldwide, as female reproductive-related neoplasms are the main cause of …

G protein-coupled receptors (GPCRs) regulate an array of fundamental biological
processes, such as growth, metabolism and homeostasis. Specifically, GPCRs are involved …

Importance Endometriosis is a common chronic gynecologic pathology with a large negative
impact on women's health. Beyond severe physical symptoms, endometriosis is also …

Endometrial carcinoma is the most common cancer of the female reproductive tract.
GPER/GPR30 is a 7‐transmembrane spanning G protein‐coupled receptor that has been …

There is an urgent clinical need for safe and effective treatment agents and therapy targets
for estrogen receptor negative (ER−) breast cancer. G protein-coupled receptor 30 (GPR30) …

Cancer is one of the most common causes of death worldwide, and its development is a
result of the complex interaction of genetic factors, environmental cues, and aging. Hormone …

Phytoestrogens are increasingly used as dietary supplements due to their suggested health
promoting properties, but also by women for breast enhancement and relief of menopausal …

Background Estrogenic signals are suggested to have protection roles in the development of
colorectal cancer (CRC). The G protein-coupled estrogen receptor (GPER) has been …

The targeted therapy for triple-negative breast cancer (TNBC) is a great challenge due to our
poor understanding on its molecular etiology. In the present study, our clinical data showed …

Lipid kinases have largely been neglected as targets in cancer, and an increasing number
of reports suggest diacylglycerol kinase alpha (DGKα) may be one with promising …