[HTML][HTML] Radiation-induced heart disease: a review of classification, mechanism and prevention

H Wang, J Wei, Q Zheng, L Meng, Y **n… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an
important component of comprehensive treatment. RT improves survival in many cancers …

Exosomes and cardiac repair after myocardial infarction

S Sahoo, DW Losordo - Circulation research, 2014 - Am Heart Assoc
Myocardial infarction is a leading cause of death among all cardiovascular diseases. The
analysis of molecular mechanisms by which the ischemic myocardium initiates repair and …

Identification of therapeutic covariant microRNA clusters in hypoxia-treated cardiac progenitor cell exosomes using systems biology

WD Gray, KM French, S Ghosh-Choudhary… - Circulation …, 2015 - Am Heart Assoc
Rationale: Myocardial infarction is a leading cause of death in developed nations, and there
remains a need for cardiac therapeutic systems that mitigate tissue damage. Cardiac …

Macrophage activation and polarization in post-infarction cardiac remodeling

A Gombozhapova, Y Rogovskaya, V Shurupov… - Journal of biomedical …, 2017 - Springer
Adverse cardiac remodeling leads to impaired ventricular function and heart failure,
remaining a major cause of mortality and morbidity in patients with acute myocardial …

A new approach for the prevention and treatment of cardiovascular disorders. Molecular hydrogen significantly reduces the effects of oxidative stress

TW LeBaron, B Kura, B Kalocayova, N Tribulova… - Molecules, 2019 - mdpi.com
Cardiovascular diseases are the most common causes of morbidity and mortality worldwide.
Redox dysregulation and a dyshomeostasis of inflammation arise from, and result in, cellular …

Diagnosis and therapeutic management of liver fibrosis by MicroRNA

T Tadokoro, A Morishita, T Masaki - International Journal of Molecular …, 2021 - mdpi.com
Remarkable progress has been made in the treatment and control of hepatitis B and C viral
infections. However, fundamental treatments for diseases in which liver fibrosis is a key …

Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated intercellular communication on chronic heart failure after …

T Yamaguchi, Y Izumi, Y Nakamura, T Yamazaki… - International journal of …, 2015 - Elsevier
Background Remote ischemic conditioning (RIC) by repeated treatment of transient limb
ischemia is a clinically applicable method for protecting the heart against injury at the time of …

Identification of circulating microRNAs for the differential diagnosis of Parkinson's disease and Multiple System Atrophy

A Vallelunga, M Ragusa, S Di Mauro… - Frontiers in cellular …, 2014 - frontiersin.org
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder which
may be misdiagnosed with atypical conditions such as Multiple System Atrophy (MSA), due …

Dynamically regulated miRNA-mRNA networks revealed by exercise

AG Tonevitsky, DV Maltseva, A Abbasi, TR Samatov… - BMC physiology, 2013 - Springer
Background MiRNAs are essential mediators of many biological processes. The aim of this
study was to investigate the dynamics of miRNA-mRNA regulatory networks during exercise …

Exosomes function in pro-and anti-angiogenesis

M Fernandes Ribeiro, H Zhu, R W. Millard… - Current …, 2013 - benthamdirect.com
Exosomes, a group of small vesicles (30-100 nm), originate when the inward budding of the
endosomal membrane forms multivesicular bodies (MVBs). Exosomes are released into the …