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Single-cell proteomics enabled by next-generation sequencing or mass spectrometry
HM Bennett, W Stephenson, CM Rose, S Darmanis - Nature Methods, 2023 - nature.com
In the last decade, single-cell RNA sequencing routinely performed on large numbers of
single cells has greatly advanced our understanding of the underlying heterogeneity of …
single cells has greatly advanced our understanding of the underlying heterogeneity of …
Applications of single-cell RNA sequencing in drug discovery and development
Single-cell technologies, particularly single-cell RNA sequencing (scRNA-seq) methods,
together with associated computational tools and the growing availability of public data …
together with associated computational tools and the growing availability of public data …
Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease
In the past decade, single-cell technologies have proliferated and improved from their
technically challenging beginnings to become common laboratory methods capable of …
technically challenging beginnings to become common laboratory methods capable of …
Single‐cell RNA sequencing technologies and applications: A brief overview
Single‐cell RNA sequencing (scRNA‐seq) technology has become the state‐of‐the‐art
approach for unravelling the heterogeneity and complexity of RNA transcripts within …
approach for unravelling the heterogeneity and complexity of RNA transcripts within …
[HTML][HTML] Embryo model completes gastrulation to neurulation and organogenesis
Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro
1, 2, 3, 4, 5, but their developmental potential is substantially extended by interactions with …
1, 2, 3, 4, 5, but their developmental potential is substantially extended by interactions with …
Advances in single-cell RNA sequencing and its applications in cancer research
D Huang, N Ma, X Li, Y Gou, Y Duan, B Liu… - Journal of hematology & …, 2023 - Springer
Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …
functional capabilities during the transition from a normal to a neoplastic state. Powerful …
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly
For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …
A human cell atlas of fetal gene expression
INTRODUCTION A reference atlas of human cell types is a major goal for the field. Here, we
set out to generate single-cell atlases of both gene expression (this study) and chromatin …
set out to generate single-cell atlases of both gene expression (this study) and chromatin …
GAGE-seq concurrently profiles multiscale 3D genome organization and gene expression in single cells
The organization of mammalian genomes features a complex, multiscale three-dimensional
(3D) architecture, whose functional significance remains elusive because of limited single …
(3D) architecture, whose functional significance remains elusive because of limited single …
RNA sequencing: new technologies and applications in cancer research
Over the past few decades, RNA sequencing has significantly progressed, becoming a
paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing …
paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing …