Strategy of develo** nucleic acid-based universal monkeypox vaccine candidates
Until May 2022, zoonotic infectious disease monkeypox (MPX) caused by the monkeypox
virus (MPXV) was one of the forgotten viruses considered to be geographically limited in …
virus (MPXV) was one of the forgotten viruses considered to be geographically limited in …
Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches
R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
Promising strategy for develo** mRNA-based universal influenza virus vaccine for human population, poultry, and pigs–focus on the bigger picture
Since the first outbreak in the 19th century influenza virus has remained emergent owing to
the huge pandemic potential. Only the pandemic of 1918 caused more deaths than any war …
the huge pandemic potential. Only the pandemic of 1918 caused more deaths than any war …
Improved global protein homolog detection with major gains in function identification
There are several hundred million protein sequences, but the relationships among them are
not fully available from existing homolog detection methods. There is an essential need for …
not fully available from existing homolog detection methods. There is an essential need for …
Timing the origin of eukaryotic cellular complexity with ancient duplications
Eukaryogenesis is one of the most enigmatic evolutionary transitions, during which simple
prokaryotic cells gave rise to complex eukaryotic cells. While evolutionary intermediates are …
prokaryotic cells gave rise to complex eukaryotic cells. While evolutionary intermediates are …
Designing multi-epitope mRNA construct as a universal influenza vaccine candidate for future epidemic/pandemic preparedness
Despite the availability of prevention and treatment strategies and advancing immunization
approaches, the influenza virus remains a global threat that continues to plague humanity …
approaches, the influenza virus remains a global threat that continues to plague humanity …
Development of a Multi-epitope Universal mRNA vaccine candidate for Monkeypox, Smallpox, and Vaccinia viruses: design and in Silico analyses
Notwithstanding the presence of a smallpox vaccine that is effective against monkeypox
(mpox), develo** a universal vaccine candidate against monkeypox virus (MPXV) is …
(mpox), develo** a universal vaccine candidate against monkeypox virus (MPXV) is …
Immunoinformatics-based multi-epitope containing fused polypeptide vaccine design against visceral leishmaniasis with high immunogenicity and TLR binding
Visceral leishmaniasis (VL) is the most lethal among all leishmaniasis diseases and remains
categorized as a neglected tropical disease (NTD). This study aimed to develop a peptide …
categorized as a neglected tropical disease (NTD). This study aimed to develop a peptide …
Molecular evidence of intertidal habitats selecting for repeated ice-binding protein evolution in invertebrates
Ice-binding proteins (IBPs) have evolved independently in multiple taxonomic groups to
improve their survival at sub-zero temperatures. Intertidal invertebrates in temperate and …
improve their survival at sub-zero temperatures. Intertidal invertebrates in temperate and …
Combing immunoinformatics with pangenome analysis to design a multiepitope subunit vaccine against Klebsiella pneumoniae K1, K2, K47, and K64
Z Wang, G Guo, Q Li, P Li, M Li, L Zhou… - Microbiology …, 2022 - Am Soc Microbiol
Klebsiella pneumoniae is an opportunistic Gram-negative bacterium that has become a
leading causative agent of nosocomial infections, mainly infecting patients with …
leading causative agent of nosocomial infections, mainly infecting patients with …