The mercapturic acid pathway is a major route for the biotransformation of xenobiotic and
endobiotic electrophilic compounds and their metabolites. Mercapturic acids (N-acetyl-l …

The selective hydrolysis of the extremely stable phosphoester, peptide and ester bonds of
molecules by bio-inspired metal-based catalysts (metallohydrolases) is required in a wide …

Density functional theory (DFT) has become a widely applied computational tool in most
chemistry fields. Because of its applicability, DFT calculations involving metal complexes are …

The family of M17 aminopeptidases (alias 'leucine aminopeptidases', M17-LAPs) utilize a
highly conserved hexameric structure and a binuclear metal center to selectively remove N …

Conspectus The selective hydrolysis of a peptide or amide bond (−(O) C–NH−) by a
synthetic metallopeptidase is required in a wide range of biological, biotechnological, and …

The palatability of protein-based food heavily relies on aminopeptidases with the ability for
bitter peptides degradation. However, there is a lack of methods for rational mining of …

The M17 aminopeptidase from the carcinogenic gastric bacterium Helicobacter pylori
(HpM17AP) is an important housekee** enzyme involved in catabolism of endogenous …

In this study, an improved dansyl‐chloride derivatization technique using a microwave
synthesizer was used for the qualitative and quantitative analyses of biogenic amine in the …

Creatininase is a key enzyme of creatinine-metabolizing pathway in mammals, and has a
great potential for diagnostic application. It catalyzes the reversible conversion of creatinine …

Nature has tailored a wide range of metalloenzymes that play a vast array of functions in all
living organisms and from which their survival and evolution depends on. These enzymes …