Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Neuron–oligodendroglial interactions in health and malignant disease
Experience sculpts brain structure and function. Activity-dependent modulation of the
myelinated infrastructure of the nervous system has emerged as a dimension of adaptive …
myelinated infrastructure of the nervous system has emerged as a dimension of adaptive …
Remote neuronal activity drives glioma progression through SEMA4F
The tumour microenvironment plays an essential role in malignancy, and neurons have
emerged as a key component of the tumour microenvironment that promotes tumourigenesis …
emerged as a key component of the tumour microenvironment that promotes tumourigenesis …
Schwann Cells as Orchestrators of Nerve Repair: Implications for Tissue Regeneration and Pathologies
RM Stassart, JA Gomez-Sanchez… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Peripheral nerves exist in a stable state in adulthood providing a rapid bidirectional
signaling system to control tissue structure and function. However, following injury …
signaling system to control tissue structure and function. However, following injury …
Neuro-Mesenchymal Interaction Mediated by a β2-Adrenergic Nerve Growth Factor Feedforward Loop Promotes Colorectal Cancer Progression
Cancer-associated fibroblasts (CAF) and nerves, components of the tumor
microenvironment, have each been shown to directly promote gastrointestinal cancers …
microenvironment, have each been shown to directly promote gastrointestinal cancers …
[HTML][HTML] GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant
Diffuse hemispheric gliomas, H3G34R/V-mutant (DHG-H3G34), are lethal brain tumors
lacking targeted therapies. They originate from interneuronal precursors; however …
lacking targeted therapies. They originate from interneuronal precursors; however …
Choroid plexus pathophysiology
This review examines the crucial roles of the choroid plexus (ChP) in central nervous system
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …
Crosstalk between the nervous system and tumor microenvironment: functional aspects and potential therapeutic strategies
L Wang, J Ge, H Han, Y Jia, Y Qin - Cancer Letters, 2024 - Elsevier
Recent advancements in understanding the tumor microenvironment (TME) have
highlighted the critical role of the nervous system in cancer progression. This review …
highlighted the critical role of the nervous system in cancer progression. This review …
Strategies to address key challenges of metallacycle/metallacage-based supramolecular coordination complexes in biomedical applications
D Xu, Y Li, S Yin, F Huang - Chemical Society Reviews, 2024 - pubs.rsc.org
Owing to their capacity for dynamically linking two or more functional molecules,
supramolecular coordination complexes (SCCs), exemplified by two-dimensional (2D) …
supramolecular coordination complexes (SCCs), exemplified by two-dimensional (2D) …
A prognostic neural epigenetic signature in high-grade glioma
Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but
clinical validation is limited. We present an epigenetically defined neural signature of …
clinical validation is limited. We present an epigenetically defined neural signature of …