Oxidative stress, protein damage and repair in bacteria

B Ezraty, A Gennaris, F Barras, JF Collet - Nature Reviews Microbiology, 2017 - nature.com
Oxidative damage can have a devastating effect on the structure and activity of proteins, and
may even lead to cell death. The sulfur-containing amino acids cysteine and methionine are …

Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies

C Chipot, F Dehez, JR Schnell, N Zitzmann… - Chemical …, 2018 - ACS Publications
Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …

The transporter classification database (TCDB): 2021 update

MH Saier Jr, VS Reddy… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Transporter Classification Database (TCDB; tcdb. org) is a freely accessible
reference resource, which provides functional, structural, mechanistic, medical and …

Quorum sensing enhances direct interspecies electron transfer in anaerobic methane production

S Zhao, S Zhu, S Liu, G Song, J Zhao… - Environmental …, 2024 - ACS Publications
Direct interspecies electron transfer (DIET) provides an innovative way to achieve efficient
methanogenesis, and this study proposes a new approach to upregulate the DIET pathway …

NMR as a tool to investigate the structure, dynamics and function of membrane proteins

B Liang, LK Tamm - Nature structural & molecular biology, 2016 - nature.com
Membrane-protein NMR occupies a unique niche for determining structures, assessing
dynamics, examining folding, and studying the binding of lipids, ligands and drugs to …

How the assembly and protection of the bacterial cell envelope depend on cysteine residues

JF Collet, SH Cho, BI Iorga, CV Goemans - Journal of Biological Chemistry, 2020 - jbc.org
The cell envelope of Gram-negative bacteria is a multilayered structure essential for
bacterial viability; the peptidoglycan cell wall provides shape and osmotic protection to the …

Disulfide bonds in protein folding and stability

MJ Feige, I Braakman, LM Hendershot - 2018 - books.rsc.org
Disulfide Bonds in Protein Folding and Stability | Oxidative Folding of Proteins: Basic
Principles, Cellular Regulation and Engineering | Books Gateway | Royal Society of Chemistry …

Bacterial thiol oxidoreductases—from basic research to new antibacterial strategies

KM Bocian-Ostrzycka, MJ Grzeszczuk… - Applied microbiology …, 2017 - Springer
The recent, rapid increase in bacterial antimicrobial resistance has become a major public
health concern. One approach to generate new classes of antibacterials is targeting …

[HTML][HTML] New insights into the pathogenicity of TMEM165 variants using structural modeling based on AlphaFold 2 predictions

D Legrand, M Herbaut, Z Durin, G Brysbaert… - Computational and …, 2023 - Elsevier
TMEM165 is a Golgi protein playing a crucial role in Mn 2+ transport, and whose mutations
in patients are known to cause Congenital Disorders of Glycosylation. Some of those …

In silico prediction of structure and function for a large family of transmembrane proteins that includes human Tmem41b

S Mesdaghi, DL Murphy, FS Rodríguez… - …, 2021 - pmc.ncbi.nlm.nih.gov
Background: Recent strides in computational structural biology have opened up an
opportunity to understand previously uncharacterised proteins. The under-representation of …