Vaccination remains our main defence against influenza, which causes substantial annual
mortality and poses a serious pandemic threat. Influenza virus evades immunity by rapidly …

The ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused devastating impacts …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated
individuals is increasingly common but rarely results in severe disease, likely due to the …

Considering the significant burden of post-acute COVID-19 conditions among patients
infected with SARS-CoV-2, we aimed to identify the risk of acute respiratory complications or …

Respiratory mucosal immunity induced by vaccination is vital for protection from coronavirus
infection in animal models. In humans, the capacity of peripheral vaccination to generate …

The COVID-19 pandemic placed the field of vaccinology squarely at the center of global
consciousness, emphasizing the vital role of vaccines as transformative public health tools …

Current COVID-19 vaccines provide robust protection against severe disease but minimal
protection against acquisition of infection. Intramuscularly administered COVID-19 vaccines …

Memory CD4 T cells are critical to human immunity, yet it is unclear whether viral
inflammation during memory formation has long-term consequences. Here, we compared …

Summary mRNA vaccines against the spike glycoprotein of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) elicit strong T cell responses. However, a clonal …

Infection with SARS-CoV-2 in humans has caused a pandemic of unprecedented
dimensions. SARS-CoV-2 is primarily transmitted through respiratory droplets and targets …