Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Cisplatin is a platinum-based chemotherapeutic that has long since been effective against a
variety of solid-cancers, substantially improving the five-year survival rates for cancer …

Doxorubicin (Dox) is an anthracycline antibiotic used to treat various cancers and shows
severe toxicity in multiple organ systems, including kidneys. Evidence shows that betaine's …

Combination chemotherapy appears to be a preferable option for some cancer patients,
especially when the medications target multiple pathways of oncogenesis; individuals …

Cardiotoxicity is one of the side effects of the anti-cancer drug doxorubicin (DOX) that limits
its clinical application. Betaine (BT) is a natural agent with promising useful effects against …

Cisplatin is a potent antineoplastic drug that is used for treatment of many solid tumors. It has
a wide range of adverse effects. Nephrotoxicity is the most common one of them. Platelet …

In this research, the effects of betaine on testicular ischemia–reperfusion were evaluated.
Forty rats were randomly divided into 4 groups of sham, torsion/detorsion (TD) …

Polyethylene terephthalate nanoplastics (PET-NPs) are utilized in the production of medical
bionic materials and the packaging of beverages. Betaine is a ubiquitous natural constituent …

Purpose Betaine is connected to various cardio-metabolic outcomes, yet its relationship with
hyperuricemia remains uncertain. We aimed to longitudinally investigate the association …

Objectives To evaluate the effect of melatonin versus placebo on the incidence of acute
kidney injury (AKI) in patients treated with polymyxin B. Methods We performed a single …