Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

Neutrophils are the most abundant innate immune cells in human circulation; however, their
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …

Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …

Particle-based drug delivery systems have a demonstrated value in osteoarthritis treatment.
Research in this area trends to develo** functional particles to improve the therapeutic …

Flavonoids are widely used as phytomedicines. Here, we report on flavonoid
phytomedicines with potential for development into prophylactics or therapeutics against …

A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

As a fundamental feature of solid surfaces, wettability is playing an increasingly important
role in our daily life. Benefitting from the inspiration of biological paradigms and the …

Multimodal treatment modalities hold great potential for cancer therapy, thus current efforts
are focusing on the development of more effective and practical synergistic therapeutic …

Microneedles have attracted increasing interest among various medical fields due to their
painless, noninvasive, and efficient way of drug delivery. However, practical applications of …