Ceramides are a class of sphingolipid that is the backbone structure for all sphingolipids,
such as glycosphingolipids and phosphosphingolipids. While being a minor constituent of …

Graves' disease (GD) is caused by an autoimmune formation of autoantibodies and
autoreactive T-cells against the thyroid stimulating hormone receptor (TSHR). The …

The accumulation of lipid droplets (LDs) and ceramides (Cer) is linked to non-alcoholic fatty
liver disease (NAFLD), regularly co-existing with type 2 diabetes and decreased immune …

The importance of personalized/precision medicine for targeted therapies and improved
outcomes both in terms of efficacy and safety in health care is by now grounded. We here …

In the race against COVID-19 for timely therapeutic developments, mass spectrometry-
based high-throughput methods have been valuable. COVID-19 manifests an extremely …

Ceramides and sphingolipids are long chain fatty acids, which are components of the
stratum corneum layer of the skin. The composition of ceramides, sphingolipids and other …

Accumulation of lipid droplets (LD) and ceramides (Cer) is associated with the pathogenesis
of metabolic dysfunction-associated steatotic liver disease (MASLD) a condition frequently …

Neutral sphingomyelinase 2 (NSM2), encoded by the phosphodiesterase 3 (SMPD3) gene,
is a key enzyme in the sphingolipid metabolism. It catalyzes the conversion of …

Eine Infektion mit dem Masernvirus kann eine schwere Immunsuppression mit erhöhter
Anfälligkeit für opportunistische Erreger auslösen, welche die vorübergehende …