L-type calcium channels couple membrane depolarization in neurons to numerous
processes including gene expression, synaptic efficacy, and cell survival. To establish the …

Sensory synapses of the visual and auditory systems must faithfully encode a wide dynamic
range of graded signals, and must be capable of sustained transmitter release over long …

Natural vision is a highly dynamic process. Frequent body, head, and eye movements
constantly bring new images onto the retina for brief periods, challenging our understanding …

Photoreceptor cells utilize ribbon synapses to transmit sensory signals at high resolution.
Ribbon synapses release neurotransmitters tonically, with a high release rate made …

RAPID calcium-dependent exocytosis underlies neurotransmitter release from nerve
terminals. Despite the fundamental importance of this process, neither the relationship …

To sustain high rates of transmitter release, synaptic terminals must rapidly re-supply
vesicles to release sites and prime them for exocytosis. Here we describe imaging of single …

COMMUNICATION among neurons occurs at specialized synaptic junctions, where
neurotransmitter is released via calcium-dependent exocytosis from the synaptic terminal of …

1. Simultaneous whole‐cell recordings in a rat brain slice preparation are described from
presynaptic terminals (calyces of Held) and postsynaptic somata which form an axosomatic …

▪ Abstract Activation of different types of G-protein-linked and ionotropic presynaptic
receptors has been shown to regulate neurotransmitter release throughout the central and …

P-type Ca 2+ channels in cerebellar Purkinje neurons were inhibited by GABA and the
GABAB receptor agonist baclofen. Inhibition of P-type Ca 2+ channel current involved …