Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases, and they affect millions of people worldwide, particularly older …

Neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease,
Huntington's disease, and multiple sclerosis affect millions of people around the world. In …

Neurodegenerative diseases (NDs) are characterized by abnormalities within neurons of the
brain or spinal cord that gradually lose function, eventually leading to cell death. Upon …

The AAA+ ATPase valosin containing protein (VCP) is essential for cell and organ
homeostasis, especially in cells of the nervous system. As part of a large network, VCP …

Autophagy degrades phagocytosed damaged organelles, misfolded proteins, and various
pathogens through lysosomes as an essential way to maintain cellular homeostasis …

The ubiquitin–proteasome system (UPS) is a multi-step process that serves as the primary
pathway for protein degradation within cells. UPS activity also plays a crucial role in …

Neurodegenerative diseases are critical in the healthcare system as patients suffer from
progressive diseases despite currently available drug management. Indeed, the growing …

Parkinson's disease (PD) is a devastating neurodegenerative disorder predominantly
affecting the elderly, characterized by the loss of dopaminergic neurons in the substantia …

Parkinson's disease (PD) is a common neurodegenerative disease that is mainly in middle-
aged people and elderly people, and the pathogenesis of PD is complex and diverse. The …

The failure of the proper protein turnover in the nervous system is mainly linked to a variety
of neurodegenerative disorders. Therefore, a better understanding of key protein …