Galectin-1 (gal-1) emerges as a potential biomarker for cancer diagnosis, prognosis, and
therapy. Its pivotal involvement spans various stages of tumor progression, including tumor …

Extracellular vesicles (EVs) harbor abundant glycans that mediate various functions, such as
intercellular communication and disease advancement, which play significant roles in …

Wheat germ agglutinin (WGA) is a heterodimer lectin having a molecular weight of 38 kDa. It
is found in wheat grains that can bind to specific carbohydrate moieties on cell surfaces …

In mammals, siglec7, an integral component of the siglecs, is principally found on the
surface of natural killer (NK) cells, macrophages, and monocytes, where it interacts with …

Engineering of extracellular vesicles (EVs) towards more efficient targeting and uptake to
specific cells has large potentials for their application as therapeutics. Carbohydrates play …

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by reduced
platelet levels and heightened susceptibility to bleeding resulting from augmented …

Extracellular vesicles (EVs) are important mediators of cell–cell communication thanks to
their ability to transfer their bioactive cargo, thus regulating a variety of physiological …

We here report the purification of a novel member of the galectin family, the β-galactoside-
binding lectin hRTL, from the marine sponge Chondrilla australiensis. The hRTL lectin is a …

Cells use glycans to encode information that modulates processes ranging from cell–cell
recognition to programmed cell death. This information is encoded within a glycocode, and …

Objective Although urinary extracellular vesicles (uEVs) have been extensively studied in
various cancers, their involvement in breast cancer (BC) remains largely unexplored. The …