Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration

Y Shao, XB Wang, JJ Zhang, ML Li, SS Wu… - Nature …, 2020‏ - nature.com
The earthworm is particularly fascinating to biologists because of its strong regenerative
capacity. However, many aspects of its regeneration in nature remain elusive. Here we …

Functional significance of earthworm clitellum in regulating the various biological aspects of cell survival and regeneration

JD Selvan Christyraj, AB Vaidhyalingham… - Developmental …, 2024‏ - Wiley Online Library
Earthworms are a highly abundant species in nature, with nearly 7000 different species
being discovered. Despite the similarities in morphology among earthworm species, their …

Transcriptome analysis of genes expressed in the earthworm Eisenia fetida in response to cadmium exposure

L Chai, Y Yang, H Yang, Y Zhao, H Wang - Chemosphere, 2020‏ - Elsevier
Eisenia fetida earthworm is an ecotoxicologically important test species to monitor various
pollutants. However, there is a little knowledge about the effects of cadmium (Cd) on …

Importance of clitellar tissue in the regeneration ability of earthworm Eudrilus eugeniae

S Paul, S Balakrishnan, A Arumugaperumal… - Functional & Integrative …, 2022‏ - Springer
Among the annelids, earthworms are renowned for their phenomenal ability to regenerate
the lost segments. The adult earthworm Eudrilus eugeniae contains 120 segments and the …

Identification of a novel collagen-like peptide by high-throughput screening for effective wound-healing therapy

C Du, Y Li, X **a, E Du, Y Lin, J Lian, C Ren, S Li… - International Journal of …, 2021‏ - Elsevier
Tissue regeneration and wound healing are still serious clinical complications globally and
lack satisfactory cures. Inspired by the impressive regeneration ability of the post-injury …

[HTML][HTML] Annotation of nerve cord transcriptome in earthworm Eisenia fetida

V Ponesakki, S Paul, DKS Mani, V Rajendiran… - Genomics data, 2017‏ - Elsevier
In annelid worms, the nerve cord serves as a crucial organ to control the sensory and
behavioral physiology. The inadequate genome resource of earthworms has prioritized the …

Transcriptomic analysis reveals the early body wall regeneration mechanism of the sea cucumber Holothuria leucospilota after artificially induced transverse fission

R Liu, X Ren, J Wang, T Chen, X Sun, T Lin, J Huang… - BMC genomics, 2023‏ - Springer
Background Sea cucumbers exhibit a remarkable ability to regenerate damaged or lost
tissues and organs, making them an outstanding model system for investigating processes …

Canonical Wnt Signaling is Involved in Anterior Regeneration of the Annelid Aeolosoma viride

CY Chen, WT Yueh, JH Chen - bioRxiv, 2020‏ - biorxiv.org
Annelids are regenerative animals, but the underlying mechanisms await to be discovered.
Because Wnt pathway is involved in animal regeneration to varying extents, we used …

Toxic responses of Sox2 gene in the regeneration of the earthworm Eisenia foetida exposed to Retnoic acid

J Tao, W Rong, X Diao, H Zhou - … and Physiology Part C: Toxicology & …, 2018‏ - Elsevier
Exogenous retinoic acid delays and disturbs the regeneration of Eisenia foetida. The stem
cell pluripotency factor, Sox2, can play a crucial role in cell reprogramming and …

Regeneration puzzle: correlations of immunity and DNA methylation in regenerative annelid models

CB da Costa, P Németh, P Engelmann - Invertebrate Survival Journal, 2024‏ - isj.unimore.it
Distinct gene expression patterns are important to various biological functions, spanning
developmental processes, wound healing, and the restoration of body parts. Moreover …