Growing up in a bubble: using germ-free animals to assess the influence of the gut microbiota on brain and behavior

P Luczynski, KA McVey Neufeld… - International Journal …, 2016 - academic.oup.com
There is a growing recognition of the importance of the commensal intestinal microbiota in
the development and later function of the central nervous system. Research using germ-free …

The intestinal microbiome in early life: health and disease

MC Arrieta, LT Stiemsma, N Amenyogbe… - Frontiers in …, 2014 - frontiersin.org
Human microbial colonization begins at birth and continues to develop and modulate in
species abundance for about 3 years, until the microbiota becomes adult-like. During the …

Host biology in light of the microbiome: ten principles of holobionts and hologenomes

SR Bordenstein, KR Theis - PLoS biology, 2015 - journals.plos.org
Groundbreaking research on the universality and diversity of microorganisms is now
challenging the life sciences to upgrade fundamental theories that once seemed …

Diversity and functional landscapes in the microbiota of animals in the wild

D Levin, N Raab, Y Pinto, D Rothschild, G Zanir… - Science, 2021 - science.org
Animals in the wild are able to subsist on pathogen-infected and poisonous food and show
immunity to various diseases. These may be due to their microbiota, yet we have a poor …

Community structure follows simple assembly rules in microbial microcosms

J Friedman, LM Higgins, J Gore - Nature ecology & evolution, 2017 - nature.com
Microorganisms typically form diverse communities of interacting species, whose activities
have tremendous impact on the plants, animals and humans they associate with. The ability …

Not all animals need a microbiome

TJ Hammer, JG Sanders, N Fierer - FEMS microbiology letters, 2019 - academic.oup.com
It is often taken for granted that all animals host and depend upon a microbiome, yet this has
only been shown for a small proportion of species. We propose that animals span a …

Multiorganismal insects: diversity and function of resident microorganisms

AE Douglas - Annual review of entomology, 2015 - annualreviews.org
All insects are colonized by microorganisms on the insect exoskeleton, in the gut and
hemocoel, and within insect cells. The insect microbiota is generally different from …

Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee

JA Ceja-Navarro, FE Vega, U Karaoz, Z Hao… - Nature …, 2015 - nature.com
The coffee berry borer (Hypothenemus hampei) is the most devastating insect pest of coffee
worldwide with its infestations decreasing crop yield by up to 80%. Caffeine is an alkaloid …

Gut microbiotas and host evolution: scaling up symbiosis

M Shapira - Trends in ecology & evolution, 2016 - cell.com
Our understanding of species evolution is undergoing restructuring. It is well accepted that
host–symbiont coevolution is responsible for fundamental aspects of biology. However, the …

Social networks predict gut microbiome composition in wild baboons

J Tung, LB Barreiro, MB Burns, JC Grenier, J Lynch… - elife, 2015 - elifesciences.org
Social relationships have profound effects on health in humans and other primates, but the
mechanisms that explain this relationship are not well understood. Using shotgun …