[PDF][PDF] Meiosis in budding yeast

GV Börner, A Hochwagen, AJ MacQueen - Genetics, 2023‏ - academic.oup.com
Meiosis is a specialized cell division program that is essential for sexual reproduction. The
two meiotic divisions reduce chromosome number by half, typically generating haploid …

Ready, SET, Go: Post-translational regulation of the histone lysine methylation network in budding yeast

RJ Separovich, MR Wilkins - Journal of Biological Chemistry, 2021‏ - jbc.org
Histone lysine methylation is a key epigenetic modification that regulates eukaryotic
transcription. Here, we comprehensively review the function and regulation of the histone …

Roles of histone post-translational modifications in meiosis

H Nie, X Kong, X Song, X Guo, Z Li, C Fan… - Biology of …, 2024‏ - academic.oup.com
Histone post-translational modifications, such as phosphorylation, methylation, acetylation,
and ubiquitination, play vital roles in various chromatin-based cellular processes. Meiosis is …

Balanced spatiotemporal arrangements of histone H3 and H4 posttranslational modifications are necessary for meiotic prophase I chromosome organization

SL Kumar, A Mohanty, A Kumari… - Journal of cellular …, 2024‏ - Wiley Online Library
Dynamic nuclear architecture and chromatin organizations are the key features of the mid‐
prophase I in mammalian meiosis. The chromatin undergoes major changes, including …

Rad61/Wpl1 (Wapl), a cohesin regulator, controls chromosome compaction during meiosis

K Challa, MS Lee, M Shinohara, KP Kim… - Nucleic acids …, 2016‏ - academic.oup.com
Meiosis-specific cohesin, required for the linking of the sister chromatids, plays a critical role
in various chromosomal events during meiotic prophase I, such as chromosome …

DOT-1.1-dependent H3K79 methylation promotes normal meiotic progression and meiotic checkpoint function in C. elegans

LI Lascarez-Lagunas, E Herruzo, A Grishok… - PLoS …, 2020‏ - journals.plos.org
Epigenetic modifiers are emerging as important regulators of the genome. However, how
they regulate specific processes during meiosis is not well understood. Methylation of …

[HTML][HTML] The Putative Histone Methyltransferase DOT1 Regulates Aflatoxin and Pathogenicity Attributes in Aspergillus flavus

L Liang, Y Liu, K Yang, G Lin, Z Xu, H Lan, X Wang… - Toxins, 2017‏ - mdpi.com
Lysine methyltransferases transfer methyl groups in specific lysine sites, which regulates a
variety of important biological processes in eukaryotes. In this study, we characterized a …

SCFCdc4 ubiquitin ligase regulates synaptonemal complex formation during meiosis

Z Zhu, MB Ismail, M Shinohara… - Life Science …, 2021‏ - life-science-alliance.org
Homologous chromosomes pair with each other during meiosis, culminating in the formation
of the synaptonemal complex (SC), which is coupled with meiotic recombination. In this …

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties

IJE Stulemeijer, D De Vos, K Van Harten, OK Joshi… - Scientific Reports, 2015‏ - nature.com
The conserved histone methyltransferase Dot1 establishes an H3K79 methylation pattern
consisting of mono-, di-and trimethylation states on histone H3 via a distributive mechanism …

Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis

A Sampathkumar, C Zhong, Y Tang, Y Fujita, M Ito… - Scientific Reports, 2024‏ - nature.com
DNA double-strand breaks (DSBs) activate DNA damage responses (DDRs) in both mitotic
and meiotic cells. A single-stranded DNA (ssDNA) binding protein, Replication protein-A …