Mendelian randomization
Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …
address causal questions about how modifiable exposures influence different outcomes …
Misinformation in and about science
Humans learn about the world by collectively acquiring information, filtering it, and sharing
what we know. Misinformation undermines this process. The repercussions are extensive …
what we know. Misinformation undermines this process. The repercussions are extensive …
Participation bias in the UK Biobank distorts genetic associations and downstream analyses
While volunteer-based studies such as the UK Biobank have become the cornerstone of
genetic epidemiology, the participating individuals are rarely representative of their target …
genetic epidemiology, the participating individuals are rarely representative of their target …
Effect of alternate day fasting combined with aerobic exercise on non-alcoholic fatty liver disease: A randomized controlled trial
Innovative non-pharmacological lifestyle strategies to treat non-alcoholic fatty liver disease
(NAFLD) are critically needed. This study compared the effects of alternate day fasting (ADF) …
(NAFLD) are critically needed. This study compared the effects of alternate day fasting (ADF) …
Socioeconomic status and child psychopathology in the United States: A meta-analysis of population-based studies
Children raised in families with low socioeconomic status (SES) are more likely to exhibit
symptoms of psychopathology. However, the strength of this association, the specific indices …
symptoms of psychopathology. However, the strength of this association, the specific indices …
[HTML][HTML] Using genetic association data to guide drug discovery and development: review of methods and applications
Evidence on the validity of drug targets from randomized trials is reliable but typically
expensive and slow to obtain. In contrast, evidence from conventional observational …
expensive and slow to obtain. In contrast, evidence from conventional observational …
On the need for a language describing distribution shifts: Illustrations on tabular datasets
Different distribution shifts require different algorithmic and operational interventions.
Methodological research must be grounded by the specific shifts they address. Although …
Methodological research must be grounded by the specific shifts they address. Although …
[HTML][HTML] Dietary fiber, atherosclerosis, and cardiovascular disease
GA Soliman - Nutrients, 2019 - mdpi.com
Background: Open Access Communication Dietary Fiber, Atherosclerosis, and
Cardiovascular Disease by Ghada A. Soliman Department of Environmental, Occupational …
Cardiovascular Disease by Ghada A. Soliman Department of Environmental, Occupational …
Multivariable Mendelian randomization and mediation
E Sanderson - Cold Spring Harbor perspectives …, 2021 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is the use of genetic variants associated with an exposure to
estimate the causal effect of that exposure on an outcome. Mediation analysis is the method …
estimate the causal effect of that exposure on an outcome. Mediation analysis is the method …
Healthy lifestyle and life expectancy in people with multimorbidity in the UK Biobank: a longitudinal cohort study
Background Whether a healthy lifestyle impacts longevity in the presence of multimorbidity is
unclear. We investigated the associations between healthy lifestyle and life expectancy in …
unclear. We investigated the associations between healthy lifestyle and life expectancy in …