Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two
types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of …

Testicular tumours in dogs are of Sertoli cell, Leydig cell or germinal origin and mixed
tumours are also frequently observed. The cellular components of mixed tumours are …

During the elongating spermatid stage of spermiogenesis, human sperm chromatin
undergoes a complex transition in which histones are extensively replaced by protamines in …

During the haploid phase of mammalian spermatogenesis, nucleosomal chromatin is
ultimately repackaged by small, highly basic protamines to generate an extremely compact …

Within the sperm nucleus the paternal genome remains functionally inert and protected
following protamination. This is marked by a structural morphogenesis that is heralded by a …

Spermatogenesis is a strictly regulated process, at both the transcriptional and the
posttranscriptional level, which allows continuous gamete production throughout adulthood …

The terminal differentiation of a keratinocyte in the epidermis involves the cessation of
proliferation and subsequent migration from the basal layer through the three suprabasal …

The setting of male-specific epigenetic information is a complex process, which involves a
major global re-organisation, as well as localized changes of the nucleus structure during …

The spermatozoon is an accessible cell which can be easily purified and therefore it is
particularly well suited for proteomic analysis. It is also an extremely differentiated cell with …

Significance: Among the 200 or so cell types that comprise mammals, spermatozoa have an
ambiguous relationship with the reactive oxygen species (ROS) inherent in the consumption …