A missing link in affect regulation: the cerebellum

MR Frazier, LJ Hoffman, H Popal… - Social Cognitive and …, 2022 - academic.oup.com
The cerebellum is one-third the size of the cerebrum yet holds twice the number of neurons.
Historically, its sole function was thought to be in the calibration of smooth movements …

The cerebellum gains weight: a systematic review of alterations in cerebellar volume and cerebro-cerebellar functional alterations in individuals with eating disorders

L Siciliano, G Olivito, M Leggio - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Background Brain imaging studies on eating disorders (EDs) often reported volumetric and
functional changes involving the cerebellum. Nevertheless, few studies performed in-depth …

The cerebellum gets social: evidence from an exploratory study of cerebellar, neurodevelopmental, and psychiatric disorders

G Olivito, L Siciliano, S Clausi, M Lupo, R Baiocco… - Biomedicines, 2023 - mdpi.com
Social prediction is a key feature of social cognition (SC), a function in which the modulating
role of the cerebellum is recognized. Accordingly, cerebellar alterations are reported in …

Cerebellar neurostimulation for boosting social and affective functions: implications for the rehabilitation of hereditary ataxia patients

A Ciricugno, V Oldrati, Z Cattaneo, M Leggio, C Urgesi… - The Cerebellum, 2024 - Springer
Beyond motor deficits, spinocerebellar ataxia (SCA) patients also suffer cognitive decline
and show socio-affective difficulties, negatively impacting on their social functioning. The …

A Virtual In Vivo Dissection and Analysis of Socioaffective Symptoms Related to Cerebellum-Midbrain Reward Circuitry in Humans

LJ Hoffman, JM Foley, JK Leong… - Journal of …, 2024 - jneurosci.org
Emerging research in nonhuman animals implicates cerebellar projections to the ventral
tegmental area (VTA) in appetitive behaviors, but these circuits have not been characterized …

Functional connectivity between the cerebellar vermis and cerebrum distinguishes early treatment response for major depressive episodes in adolescents

L Wang, P Zhao, J Zhang, R Zhang, J Liu… - Journal of Affective …, 2023 - Elsevier
Background The absence of biomarkers for predicting treatment response in adolescent
mood disorder calls for further research. The vermis, a component of the cerebellum, is …

The role of the posterior cerebellum in dysfunctional social sequencing

F Van Overwalle, C Baeken, S Campanella… - The Cerebellum, 2021 - Springer
Recent advances in social neuroscience have highlighted the critical role of the cerebellum
in social cognition, and especially the posterior cerebellum. Studies have supported the …

Aberrant cerebello-cerebral connectivity in remitted bipolar patients 1 and 2: new insight into understanding the cerebellar role in mania and hypomania

G Olivito, M Lupo, A Gragnani, M Saettoni, L Siciliano… - The Cerebellum, 2022 - Springer
Bipolar disorder (BD) is a major mental illness characterized by periods of (hypo) mania and
depression with inter-episode remission periods. Functional studies in BD have consistently …

The role of the cerebellum in sequencing and predicting social and non-social events in patients with bipolar disorder

L Siciliano, G Olivito, M Lupo, N Urbini… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Advances in the operational mode of the cerebellum indicate a role in
sequencing and predicting non-social and social events, crucial for individuals to optimize …

[HTML][HTML] Altered cerebellar gray matter and cerebellar-cortex resting-state functional connectivity in patients with bipolar disorder Ⅰ

L Cui, H Li, JB Li, H Zeng, Y Zhang, W Deng… - Journal of Affective …, 2022 - Elsevier
Background Bipolar disorder (BP) is a common psychiatric disorder characterized by
extreme fluctuations in mood. Recent studies have indicated the involvement of cerebellum …