Despite significant advances in its detection, understanding and management, atrial
fibrillation (AF) remains a highly prevalent cardiac arrhythmia with a major impact on …

Atrial fibrillation (AF) is the most common sustained arrhythmia in humans. The mechanisms
that govern AF initiation and persistence are highly complex, of dynamic nature, and involve …

Catheter ablation therapy for persistent atrial fibrillation (AF) typically includes pulmonary
vein isolation (PVI) and may include additional ablation lesions that target patient-specific …

Aims Catheter ablation is an effective technique for terminating atrial arrhythmia. However,
given a high atrial fibrillation (AF) recurrence rate, optimal ablation strategies have yet to be …

Research has indicated that atrial fibrillation (AF) ablation failure is related to the presence
of atrial fibrosis. However it remains unclear whether this information can be successfully …

Aims Treatments for persistent atrial fibrillation (AF) offer limited efficacy. One potential
strategy aims to return the right atrium (RA) to sinus rhythm (SR) by ablating interatrial …

Pulmonary vein isolation (PVI) with radiofrequency ablation (RFA) is the cornerstone of atrial
fibrillation (AF) therapy, but few strategies exist for when it fails. To guide RFA, phase …

Computational simulations of cardiac electrophysiology provide detailed information on the
depolarization phenomena at different spatial and temporal scales. With the development of …

Over the last decade, the state‐of‐the‐art in cardiac computational modelling has
progressed rapidly. The electrophysiological function of the heart can now be simulated with …

Arrhythmias in cardiac tissue are generally associated with irregular electrical wave
propagation in the heart. Cardiac tissue is formed by a discrete cell network, which is often …