Computational modeling of cardiac valve function and intervention

W Sun, C Martin, T Pham - Annual review of biomedical …, 2014‏ - annualreviews.org
In the past two decades, major advances have been made in the clinical evaluation and
treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging …

Cardioband, a transcatheter surgical-like direct mitral valve annuloplasty system: early results of the feasibility trial

F Maisano, M Taramasso, G Nickenig… - European heart …, 2016‏ - academic.oup.com
Aims Cardioband system is a direct annuloplasty adjustable device that is implanted in the
beating heart on the posterior annulus under fluoroscopic and transoesophageal …

Applications of computational modeling in cardiac surgery

LC Lee, M Genet, AB Dang, L Ge… - Journal of Cardiac …, 2014‏ - Wiley Online Library
Although computational modeling is common in many areas of science and engineering,
only recently have advances in experimental techniques and medical imaging allowed this …

Distribution of normal human left ventricular myofiber stress at end diastole and end systole: a target for in silico design of heart failure treatments

M Genet, LC Lee, R Nguyen… - Journal of applied …, 2014‏ - journals.physiology.org
Ventricular wall stress is believed to be responsible for many physical mechanisms taking
place in the human heart, including ventricular remodeling, which is frequently associated …

A coupled mitral valve—left ventricle model with fluid–structure interaction

H Gao, L Feng, N Qi, C Berry, BE Griffith… - Medical engineering & …, 2017‏ - Elsevier
Understanding the interaction between the valves and walls of the heart is important in
assessing and subsequently treating heart dysfunction. This study presents an integrated …

Human cardiac function simulator for the optimal design of a novel annuloplasty ring with a sub-valvular element for correction of ischemic mitral regurgitation

B Baillargeon, I Costa, JR Leach, LC Lee… - Cardiovascular …, 2015‏ - Springer
Ischemic mitral regurgitation is associated with substantial risk of death. We sought to:(1)
detail significant recent improvements to the Dassault Systèmes human cardiac function …

A novel left heart simulator for the multi-modality characterization of native mitral valve geometry and fluid mechanics

JP Rabbah, N Saikrishnan, AP Yoganathan - Annals of biomedical …, 2013‏ - Springer
Numerical models of the mitral valve have been used to elucidate mitral valve function and
mechanics. These models have evolved from simple two-dimensional approximations to …

A computational pipeline for patient-specific prediction of the postoperative mitral valve functional state

H Liu, NT Simonian, AM Pouch… - Journal of …, 2023‏ - asmedigitalcollection.asme.org
While mitral valve (MV) repair remains the preferred clinical option for mitral regurgitation
(MR) treatment, long-term outcomes remain suboptimal and difficult to predict. Furthermore …

Finite element analysis of patient-specific mitral valve with mitral regurgitation

T Pham, F Kong, C Martin, Q Wang, C Primiano… - Cardiovascular …, 2017‏ - Springer
Functional mitral regurgitation (FMR) is a significant complication of left ventricular
dysfunction and strongly associated with a poor prognosis. In this study, we developed a …

Modelling mitral valvular dynamics–current trend and future directions

H Gao, N Qi, L Feng, X Ma, M Danton… - International Journal …, 2017‏ - Wiley Online Library
Dysfunction of mitral valve causes morbidity and premature mortality and remains a leading
medical problem worldwide. Computational modelling aims to understand the biomechanics …