Resurrection of 2′-5′-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication
The prenylated form of the human 2′-5′-oligoadenylate synthetase 1 (OAS1) protein has
been shown to potently inhibit the replication of Severe Acute Respiratory Syndrome …
been shown to potently inhibit the replication of Severe Acute Respiratory Syndrome …
Genomic transfers help to decipher the ancient evolution of filoviruses and interactions with vertebrate hosts
DJ Taylor, MH Barnhart - PLoS pathogens, 2024 - journals.plos.org
Although several filoviruses are dangerous human pathogens, there is conflicting evidence
regarding their origins and interactions with animal hosts. Here we attempt to improve this …
regarding their origins and interactions with animal hosts. Here we attempt to improve this …
Endogenous viral elements: insights into data availability and accessibility
Endogenous viral elements (EVEs) are remnants of viral genetic material endogenized into
the host genome. They have, in the last decades, attracted attention for their role as potential …
the host genome. They have, in the last decades, attracted attention for their role as potential …
Evolution of the Cytomegalovirus RL11 gene family in Old World monkeys and Great Apes
Cytomegalovirus (CMV) is a genus of herpesviruses, members of which share a long history
of coevolution with their primate hosts including New World monkeys, Old World monkeys …
of coevolution with their primate hosts including New World monkeys, Old World monkeys …
Exploring the role of endogenous retroviruses in seasonal reproductive cycles: a case study of the ERV-V envelope gene in mink
Y Zhang, G Wang, Y Zhu, X Cao, F Liu, H Li… - Frontiers in Cellular and …, 2024 - frontiersin.org
Introduction Endogenous retroviruses (ERVs), which originated from exogenous retroviral
infections of germline cells millions of years ago and were inherited by subsequent …
infections of germline cells millions of years ago and were inherited by subsequent …
Endogenous Bornavirus-like Elements in Bats: Evolutionary Insights from the Conserved Riboviral L-Gene in Microbats and Its Antisense Transcription in Myotis …
Bats are ecologically diverse vertebrates characterized by their ability to host a wide range
of viruses without apparent illness and the presence of numerous endogenous viral …
of viruses without apparent illness and the presence of numerous endogenous viral …
Mutational Constraint Analysis Workflow for Overlap** Short Open Reading Frames and Genomic Neighbours
Understanding the dark genome is a priority task following the complete sequencing of the
human genome. Short open reading frames (sORFs) are a group of largely unexplored …
human genome. Short open reading frames (sORFs) are a group of largely unexplored …
detectEVE: fast, sensitive and precise detection of endogenous viral elements in genomic data
N Brait, T Hackl, S Lequime - bioRxiv, 2024 - biorxiv.org
Endogenous viral elements (EVEs) are fragments of viral genomic material embedded
within the host genome. Retroviruses contribute to the majority of EVEs due to their genomic …
within the host genome. Retroviruses contribute to the majority of EVEs due to their genomic …