Colorectal cancer (CRC) is the third most diagnosed malignancy and a major leading cause
of cancer-related deaths worldwide. Despite advances in therapeutic regimens, the number …

Rational drug design implies usage of molecular modeling techniques such as
pharmacophore modeling, molecular dynamics, virtual screening, and molecular docking to …

After lung cancer, breast cancer (BC) is the most frequent cause of cancer death among
women, worldwide. Although advances in screening approaches and targeted therapeutic …

Computational methods have been widely used in drug design. The recent developments in
machine learning techniques and the ever-growing chemical and biological databases are …

Abstract Epidermal Growth Factor Receptor (EGFR), and Human EGFR-related Receptor 2
(HER2) are validated targets for anticancer drugs which provide synergistic effects when …

Protein kinases (in this case, HER-2 and EGFR) are involved in cancer-related diseases.
Some reports have shown unique CoMFA models using the sum of activities expressed as …

Breast cancer is one of the common causes of death noticed in women globally. In order to
find effective therapeutics, the current investigation has focussed on identifying candidate …

Procedures for inhibiting hormone receptor activation include administering to a subject in
need of hormone receptor inhibition a compound having a chemical structure of a molecule …