[HTML][HTML] Allergen immunotherapy: past, present and future

SR Durham, MH Shamji - Nature Reviews Immunology, 2023 - nature.com
Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

Advances and highlights in allergic rhinitis

Y Zhang, F Lan, L Zhang - Allergy, 2021 - Wiley Online Library
Allergic rhinitis (AR) is a growing public health, medical and economic problem worldwide.
The current review describes the major discoveries related to AR during the past 2 years …

Heterogeneity of type 2 innate lymphoid cells

H Spits, J Mjösberg - Nature Reviews Immunology, 2022 - nature.com
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …

Update on pathomechanisms and treatments in allergic rhinitis

Y Zhang, F Lan, L Zhang - Allergy, 2022 - Wiley Online Library
Allergic rhinitis (AR) is a global health problem with increasing prevalence and association
with an enormous medical and socioeconomic burden. New recognition of immune cells …

Cellular and molecular mechanisms of allergic asthma

ZI Komlósi, W van de Veen, N Kovács, G Szűcs… - Molecular aspects of …, 2022 - Elsevier
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Advances and highlights in biomarkers of allergic diseases

I Ogulur, Y Pat, O Ardicli, E Barletta, L Cevhertas… - Allergy, 2021 - Wiley Online Library
During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …

Early-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females

CM Capelle, S Ciré, F Hedin, M Hansen… - Nature …, 2023 - nature.com
Neuroinflammation in the brain contributes to the pathogenesis of Parkinson's disease (PD),
but the potential dysregulation of peripheral immunity has not been systematically …

One hundred and ten years of allergen immunotherapy: a journey from empiric observation to evidence

O Pfaar, J Bousquet, SR Durham, J Kleine‐Tebbe… - Allergy, 2022 - Wiley Online Library
One hundred and ten years after Noon's first clinical report of the subcutaneous application
of allergen extracts, allergen immunotherapy (AIT) has evolved as the most important pillar …

[HTML][HTML] Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms

JJ Yepes-Nuñez, GH Guyatt… - Journal of Allergy and …, 2023 - Elsevier
Background Atopic dermatitis (AD, eczema) is driven by a combination of skin barrier
defects, immune dysregulation, and extrinsic stimuli such as allergens, irritants, and …

Immunological responses and biomarkers for allergen-specific immunotherapy against inhaled allergens

MH Shamji, JA Layhadi, H Sharif, M Penagos… - The Journal of Allergy …, 2021 - Elsevier
Long-term efficacy that occurs with allergen immunotherapy of proven value is associated
with decreases in IgE-dependent activation of mast cells and tissue eosinophilia. This …