Hydrogels as artificial matrices for cell seeding in microfluidic devices
Hydrogel-based artificial scaffolds play a vital role in shifting in vitro models from two-
dimensional (2D) cell culture to three-dimensional (3D) cell culture. Microfluidic 3D cell …
dimensional (2D) cell culture to three-dimensional (3D) cell culture. Microfluidic 3D cell …
Microfluidic lumen-based systems for advancing tubular organ modeling
Microfluidic lumen-based systems are microscale models that recapitulate the anatomy and
physiology of tubular organs. These technologies can mimic human pathophysiology and …
physiology of tubular organs. These technologies can mimic human pathophysiology and …
Microfluidic tumor-on-a-chip model to evaluate the role of tumor environmental stress on NK cell exhaustion
Solid tumors generate a suppressive environment that imposes an overwhelming burden on
the immune system. Nutrient depletion, waste product accumulation, hypoxia, and pH …
the immune system. Nutrient depletion, waste product accumulation, hypoxia, and pH …
Nano-liter perfusion microfluidic device made entirely by two-photon polymerization for dynamic cell culture with easy cell recovery
HJ McLennan, AJ Blanch, SJ Wallace, LJ Ritter… - Scientific Reports, 2023 - nature.com
Polydimethylsiloxane (PDMS) has been the material of choice for microfluidic applications in
cell biology for many years, with recent advances encompassing nano-scaffolds and surface …
cell biology for many years, with recent advances encompassing nano-scaffolds and surface …
Scaffold-based 3D cell culture models in cancer research
Abstract Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer
research, offering significant advantages over traditional two-dimensional (2D) cell culture …
research, offering significant advantages over traditional two-dimensional (2D) cell culture …
Microfluidic Platforms for Real‐Time In Situ Monitoring of Biomarkers for Cellular Processes
C Lou, H Yang, Y Hou, H Huang, J Qiu… - Advanced …, 2024 - Wiley Online Library
Cellular processes are mechanisms carried out at the cellular level that are aimed at
guaranteeing the stability of the organism they comprise. The investigation of cellular …
guaranteeing the stability of the organism they comprise. The investigation of cellular …
Engineering organ-on-a-chip to accelerate translational research
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
Recent progress in microfluidic models of the blood-brain barrier
L Jiang, S Li, J Zheng, Y Li, H Huang - Micromachines, 2019 - mdpi.com
The blood-brain barrier (BBB) is a critical physical and chemical barrier that maintains brain
homeostasis. Researchers in academia and industry are highly motivated to develop …
homeostasis. Researchers in academia and industry are highly motivated to develop …
Microphysiological head and neck cancer model identifies novel role of lymphatically secreted monocyte migration inhibitory factor in cancer cell migration and …
Regional metastasis of head and neck cancer (HNC) is prevalent (approximately 50% of
patients at diagnosis), yet the underlying drivers and mechanisms of lymphatic spread …
patients at diagnosis), yet the underlying drivers and mechanisms of lymphatic spread …
Primary head and neck tumour-derived fibroblasts promote lymphangiogenesis in a lymphatic organotypic co-culture model
Background In head and neck cancer, intratumour lymphatic density and tumour
lymphangiogenesis have been correlated with lymphatic metastasis, making …
lymphangiogenesis have been correlated with lymphatic metastasis, making …