Response of cells and tissues to shear stress

JA Espina, MH Cordeiro, M Milivojevic… - Journal of Cell …, 2023 - journals.biologists.com
Shear stress is essential for normal physiology and malignancy. Common physiological
processes–such as blood flow, particle flow in the gut, or contact between migratory cell …

Sustained oscillations of epithelial cell sheets

G Peyret, R Mueller, J d'Alessandro, S Begnaud… - Biophysical journal, 2019 - cell.com
Morphological changes during development, tissue repair, and disease largely rely on
coordinated cell movements and are controlled by the tissue environment. Epithelial cell …

Theory of mechanochemical patterning and optimal migration in cell monolayers

D Boocock, N Hino, N Ruzickova, T Hirashima… - Nature physics, 2021 - nature.com
Collective cell migration offers a rich field of study for non-equilibrium physics and cellular
biology, revealing phenomena such as glassy dynamics, pattern formation and active …

Mechanical oscillations in 2D collective cell migration: the elastic turbulence

I Pajic-Lijakovic, M Milivojevic - Frontiers in Physics, 2020 - frontiersin.org
Various types of mechanical waves, such as propagative waves and standing waves, are
observed during 2D collective cell migration. Propagative waves are generated during …

Emergence, Pattern, and Frequency of Spontaneous Waves in Spreading Epithelial Monolayers

X Yin, YQ Liu, LY Zhang, D Liang, GK Xu - Nano Letters, 2024 - ACS Publications
A striking phenomenon of collective cell motion is that they can exhibit a spontaneously
emerging wave during epithelia expansions. However, the fundamental mechanism …

Interplay between mechanochemical patterning and glassy dynamics in cellular monolayers

D Boocock, T Hirashima, E Hannezo - PRX Life, 2023 - APS
Living tissues are characterized by an intrinsically mechanochemical interplay of active
physical forces and complex biochemical signaling pathways. Either feature alone can give …

Size-dependent patterns of cell proliferation and migration in freely-expanding epithelia

MA Heinrich, R Alert, JM LaChance, TJ Zajdel… - Elife, 2020 - elifesciences.org
The coordination of cell proliferation and migration in growing tissues is crucial in
development and regeneration but remains poorly understood. Here, we find that, while …

Pulsating active matter

Y Zhang, É Fodor - Physical Review Letters, 2023 - APS
We reveal that the mechanical pulsation of locally synchronized particles is a generic route
to propagate deformation waves. We consider a model of dense repulsive particles whose …

Active chemo-mechanical feedbacks dictate the collective migration of cells on patterned surfaces

C Fang, J Yao, Y Zhang, Y Lin - Biophysical Journal, 2022 - cell.com
Recent evidence has demonstrated that, when cultured on micro-patterned surfaces, living
cells can move in a coordinated manner and form distinct migration patterns, including …

Spatiotemporal oscillation in confined epithelial motion upon fluid-to-solid transition

J Yu, P Cai, X Zhang, T Zhao, L Liang, S Zhang, H Liu… - ACS …, 2021 - ACS Publications
Fluid-to-solid phase transition in multicellular assembly is crucial in many developmental
biological processes, such as embryogenesis and morphogenesis. However, biomechanical …