Glucocorticoids are widely used to suppress inflammation or the immune system. High
doses and long-term use of glucocorticoids lead to an important and common iatrogenic …

Ectopic ACTH syndrome (EAS) is rare but is frequently a severe condition because of the
intensity of the hypercortisolism that may be dissociated from the tumoral condition. EAS …

Cushing's syndrome is caused by prolonged exposure to elevated cortisol levels. The most
common form of endogenous Cushing's syndrome is Cushing's disease, which results from …

Cushing's syndrome (CS) results from chronic exposure to cortisol excess, produced by the
adrenal cortex. Hypercortisolism predisposes to psychiatric and neurocognitive disorders …

Introduction Solid organ transplantation is an established therapy for end-stage organ
failure. Both pre-transplantation bone disease and immunosuppressive regimens result in …

Glucocorticoids (GCs) are the final effector products of a neuroendocrine HPA/HPI axis
governing energy balance and stress response in vertebrates. From a physiological point of …

Decades of research have demonstrated that physical stress (PS) stimulates bone
remodeling and affects bone structure and function through complex mechanotransduction …

For decades, there has been speculation regarding the interaction of cannabinoids with
glucocorticoid systems. Given the functional redundancy between many of the physiological …

In a cohort study of 182 consecutive patients with active endogenous Cushing's syndrome,
the only predictor of fracture occurrence after adjustment for age, gender bone mineral …

Cushing's disease is a rare chronic disease caused by a pituitary adenoma, which leads to
excess secretion of adrenocorticotropic hormone (ACTH). The over-production of ACTH …