Review of the cosolvency models for predicting drug solubility in solvent mixtures: an update

A Jouyban - Journal of Pharmacy & Pharmaceutical …, 2019 - journals.library.ualberta.ca
The cosolvency models frequently used in solubility data modeling of drugs in mixed
solvents were reviewed and their accuracies for calculating the solubility of solutes were …

Review of the cosolvency models for predicting solubility of drugs in water-cosolvent mixtures

A Jouyban - Journal of Pharmacy & Pharmaceutical …, 2008 - journals.library.ualberta.ca
The cosolvency models presented from 1960 to 2007 were reviewed and their accuracies
for correlating and/or predicting the solubility of drugs in water-cosolvent mixtures were …

Mathematical derivation of the Jouyban-Acree model to represent solute solubility data in mixed solvents at various temperatures

A Jouyban, WE Acree Jr - Journal of Molecular Liquids, 2018 - Elsevier
The solubility of a solute is an important physico-chemical property of drugs/chemicals and
is highly in demand in the industry. Addition of the second solvent is a common procedure to …

[LIBRO][B] Handbook of solubility data for pharmaceuticals

A Jouyban - 2009 - taylorfrancis.com
Aqueous solubility is one of the major challenges in the early stages of drug discovery. One
of the most common and effective methods for enhancing solubility is the addition of an …

Solubility of carvedilol in ethanol+ propylene glycol mixtures at various temperatures

S Vahdati, A Shayanfar, J Hanaee… - Industrial & …, 2013 - ACS Publications
Solubilities of carvedilol (CVD) in binary mixtures of (ethanol+ propylene glycol (PG)) at
298.2, 303.2, 308.2, and 313.2 K are reported. The modified versions of the van't Hoff and …

Comment on “Measurement and Correlation of Solubilities of (Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetic Acid in Different Pure Solvents and Binary Mixtures of …

A Jouyban, MAA Fakhree… - Journal of Chemical & …, 2012 - ACS Publications
In a recent paper in this journal, Zhou et al. 1 reported the experimental solubility data of (Z)-
2-(2-aminothiazol-4-yl)-2-methoxyiminoacetic acid (a pharmaceutical intermediate …

A simple relationship between dielectric constant of mixed solvents with solvent composition and temperature

A Jouyban, S Soltanpour, HK Chan - International journal of pharmaceutics, 2004 - Elsevier
A simple computational method for calculating dielectric constants of solvent mixtures based
on Redlich-Kister extension was proposed. The model was applied to the experimental …

Comparison of models for describing multiple peaks in solubility profiles

A Jouyban-Gharamaleki, WE Acree Jr - International journal of …, 1998 - Elsevier
A model derived from the combined nearly ideal binary solvent/Redlich-Kister equation
(CNIBS/RK) for reproducing the experimental solubility curve in mixed solvent systems …

Comparison of various cosolvency models for calculating solute solubility in water–cosolvent mixtures

A Jouyban-Gharamaleki, L Valaee… - International journal of …, 1999 - Elsevier
Previously published cosolvency models are critically evaluated in terms of their ability to
mathematically correlate solute solubility in binary solvent mixtures as a function of solvent …

Experimental and computational methods pertaining to drug solubility

A Jouyban, MAA Fakhree - Toxicity and drug testing, 2012 - books.google.com
Solubility of a drug is one of its important physico-chemical properties. More attention has
been paid to the aqueous solubility since water is the unique solvent of biological systems. It …