Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients

Y Sherer, A Gorstein, MJ Fritzler, Y Shoenfeld - Seminars in arthritis and …, 2004 - Elsevier
OBJECTIVE: Description of the various autoantibodies that can be detected in patients with
systemic lupus erythematosus (SLE). METHODS: A literature review, using the terms …

The use of laboratory tests in the diagnosis of SLE

W Egner - Journal of clinical pathology, 2000 - jcp.bmj.com
Systemic lupus erythematosus (SLE) is a protean autoimmune disease where
autoantibodies are frequently targeted against intracellular antigens of the cell nucleus …

Free DNA in the serum of cancer patients and the effect of therapy

SA Leon, B Shapiro, DM Sklaroff, MJ Yaros - Cancer research, 1977 - AACR
A radioimmunoassay for ng quantities of DNA was developed.[125I] Iododeoxyuridine-
labeled DNA was used as the antigen, and the serum of a lupus erythematosus patient …

Determination of circulating DNA levels in patients with benign or malignant gastrointestinal disease

B Shapiro, M Chakrabarty, EM Cohn, SA Leon - Cancer, 1983 - Wiley Online Library
Previous studies showed that patients with neoplasms of various types and origins have
abnormally high concentration of DNA in their serum. The current work compares circulating …

Assessment of antibodies to double‐stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor …

PJ Charles, RJT Smeenk, J De Jong… - … : Official Journal of …, 2000 - Wiley Online Library
Objective To compare the incidence of anti–double‐stranded DNA (anti‐dsDNA) antibodies
in rheumatoid arthritis (RA) patients receiving either single or multiple doses of a chimeric …

Clinical significance of anti-dsDNA antibody isotypes: IgG/IgM ratio of anti-dsDNA antibodies as a prognostic marker for lupus nephritis

F Förger, T Matthias, M Oppermann, H Becker… - Lupus, 2004 - journals.sagepub.com
The objective of this paper is to investigate the association between patterns of anti-dsDNA
antibody isotypes and specific clinical manifestations (categorized in renal, musculoskeletal …

Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: correlation …

M Okamura, Y Kanayama, K Amastu… - Annals of the …, 1993 - ard.bmj.com
The correlation between renal histology and class specific (IgG and IgM) antibodies to
double stranded DNA (dsDNA) and single stranded DNA (ssDNA) was studied by enzyme …

Lupus nephritis: classification, prognosis, immunopathogenesis, and treatment

J Golbus, WJ McCune - Rheumatic Disease Clinics of North America, 1994 - Elsevier
Nephritis was first recognized as a component of systemic lupus erythematosus (SLE) by Sir
William Osler. Long considered rare, it was not until the 1940s that the prevalence and …

Antibodies to DN

BD Stollar, EW Voss - Critical Reviews in Biochemistry, 1986 - Taylor & Francis
The study of anti-DNA antibodies has several motivations. One derives from the role of anti-
DNA antibody formation as part of an autoimmune response that is characteristic of the …

Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus

F Ebling, BH Hahn - Arthritis & Rheumatism: Official Journal of …, 1980 - Wiley Online Library
Abstract Sera from MRL/1, BXSB, and NZB/NZW mice, which develop IgG antibodies to DNA
and glomerular deposits of DNA‐antiDNA immune complexes, were studied by isoelectric …