The protein corona from nanomedicine to environmental science
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …
materials when they are exposed to biological environments, altering their physiochemical …
Obstacles and opportunities in a forward vision for cancer nanomedicine
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …
circulation to target tumours while sparing healthy tissues the toxicity of classic …
Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
Protein nanoparticles in drug delivery: animal protein, plant proteins and protein cages, albumin nanoparticles
E Kianfar - Journal of Nanobiotechnology, 2021 - Springer
In this article, we will describe the properties of albumin and its biological functions, types of
sources that can be used to produce albumin nanoparticles, methods of producing albumin …
sources that can be used to produce albumin nanoparticles, methods of producing albumin …
Nanodelivery of nucleic acids
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …
Precision drug delivery to the central nervous system using engineered nanoparticles
Abstract Development of novel therapies for central nervous system (CNS) disorders has
experienced a high failure rate in clinical trials owing to unsatisfactory efficacy and adverse …
experienced a high failure rate in clinical trials owing to unsatisfactory efficacy and adverse …
The ancillary effects of nanoparticles and their implications for nanomedicine
Nanoparticles are often engineered as a scaffolding system to combine targeting, imaging
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
and/or therapeutic moieties into a unitary agent. However, mostly overlooked, the …
Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
In vitro incubation of nanomaterials with plasma offer insights on biological interactions, but
cannot fully explain the in vivo fate of nanomaterials. Here, we use a library of polymer …
cannot fully explain the in vivo fate of nanomaterials. Here, we use a library of polymer …
A decade of the protein corona
In this Perspective, we reflect on a decade of research on the protein corona and
contemplate its broad implications for future science and engineering at the bio–nano …
contemplate its broad implications for future science and engineering at the bio–nano …
The effects of protein corona on in vivo fate of nanocarriers
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …