Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically …
Genetically encoded calcium indicators for visualizing dynamic cellular activity have greatly
expanded our understanding of the brain. However, owing to the light-scattering properties …
expanded our understanding of the brain. However, owing to the light-scattering properties …
Approaches to manipulating microRNAs in neurogenesis
H Zhang, B Shykind, T Sun - Frontiers in neuroscience, 2013 - frontiersin.org
Neurogenesis in the nervous system is regulated by both protein coding genes and non-
coding RNA molecules. microRNAs (miRNAs) are endogenous small non-coding RNAs and …
coding RNA molecules. microRNAs (miRNAs) are endogenous small non-coding RNAs and …
Targeted in vivo genetic manipulation of the mouse or rat brain by in utero electroporation with a triple-electrode probe
This protocol is an extension to: Nat. Protoc. 1, 1552–1558 (2006); doi: 10.1038/nprot.
2006.276; published online 9 November 2006 This article describes how to reliably …
2006.276; published online 9 November 2006 This article describes how to reliably …
Targeted approaches to delineate neuronal morphology during early development
B Liu, Y Li, M Ren, X Li - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Understanding the developmental changes that affect neurons is a key step in exploring the
assembly and maturation of neural circuits in the brain. For decades, researchers have used …
assembly and maturation of neural circuits in the brain. For decades, researchers have used …
Dentate granule neurons generated during perinatal life display distinct morphological features compared with later-born neurons in the mouse hippocampus
T Kerloch, S Clavreul, A Goron, DN Abrous… - Cerebral …, 2019 - academic.oup.com
In nonhuman mammals and in particular in rodents, most granule neurons of the dentate
gyrus (DG) are generated during development and yet little is known about their properties …
gyrus (DG) are generated during development and yet little is known about their properties …
An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration
A transcriptional programme initiated by the proneural factors Neurog2 and Ascl1 controls
successive steps of neurogenesis in the embryonic cerebral cortex. Previous work has …
successive steps of neurogenesis in the embryonic cerebral cortex. Previous work has …
The oxygen sensor PHD2 controls dendritic spines and synapses via modification of filamin A
I Segura, C Lange, E Knevels, A Moskalyuk, R Pulizzi… - Cell reports, 2016 - cell.com
Neuronal function is highly sensitive to changes in oxygen levels, but how hypoxia affects
dendritic spine formation and synaptogenesis is unknown. Here we report that hypoxia …
dendritic spine formation and synaptogenesis is unknown. Here we report that hypoxia …
Rnd3 coordinates early steps of cortical neurogenesis through actin-dependent and-independent mechanisms
The generation of neurons by neural stem cells is a highly choreographed process that
requires extensive and dynamic remodelling of the cytoskeleton at each step of the process …
requires extensive and dynamic remodelling of the cytoskeleton at each step of the process …
Alterations to dendritic spine morphology, but not dendrite patterning, of cortical projection neurons in Tc1 and Ts1Rhr mouse models of Down syndrome
Down Syndrome (DS) is a highly prevalent developmental disorder, affecting 1/700 births.
Intellectual disability, which affects learning and memory, is present in all cases and is …
Intellectual disability, which affects learning and memory, is present in all cases and is …
Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation
Complex interactions between networks of astrocytes and neurons are beginning to be
appreciated, but remain poorly understood. Transgenic mice expressing fluorescent protein …
appreciated, but remain poorly understood. Transgenic mice expressing fluorescent protein …