Innate and adaptive immune cell activation and infiltration is the key characteristic of tissue
inflammation. The innate immune system is the front line of host defense in which innate …

Reactive oxygen species (ROS) are a group of highly reactive chemicals containing oxygen
produced either exogenously or endogenously. ROS are related to a wide variety of human …

Regulatory T (Treg) cells, although vital for immune homeostasis, also represent a major
barrier to anti-cancer immunity, as the tumour microenvironment (TME) promotes the …

Nanovaccines have emerged as promising alternatives or complements to conventional
cancer treatments. Despite the progresses, specific co‐delivery of antigen and adjuvant to …

The innate immune system relies on its capacity to rapidly detect invading pathogenic
microbes as foreign and to eliminate them. The discovery of Toll-like receptors (TLRs) …

Estrogen plays a fundamental role in skeletal growth and bone homeostasis in both men
and women. Although remarkable progress has been made in our understanding of how …

Oxidative stress may regulate cellular function in multiple pathological conditions, including
atherosclerosis. One feature of the atherosclerotic plaque is calcium mineral deposition …

The activation of dendritic cells, necessary for the initiation of primary and secondary
immune responses, can be induced by endogenous danger signals—released by tissues …

Oxidants such as H2O2 are connected to lymphocyte activation, but the molecular
mechanisms behind this phenomenon are less clear. Here, I review data suggesting that by …

Wound healing requires a fine balance between the positive and deleterious effects of
reactive oxygen species (ROS); a group of extremely potent molecules, rate limiting in …