Radiolabeled nanomaterial for cancer diagnostics and therapeutics: principles and concepts
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …
Prospects of nanoparticle-based radioenhancement for radiotherapy
Radiotherapy is a key pillar of solid cancer treatment. Despite high level of conformal dose
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …
deposition, radiotherapy is limited due to co-irradiation of organs-at risk and subsequent …
Self-therapeutic nanomaterials: Applications in biology and medicine
Over past decades, nanotechnology has contributed to the biomedical field in areas
including detection, diagnosis, and drug delivery via opto-electronic properties or …
including detection, diagnosis, and drug delivery via opto-electronic properties or …
Tailoring radiotherapies and nanotechnology for targeted treatment of solid tumors
Existing anticancer therapeutic modalities in clinical settings lack efficacy and fail to
completely cure cancers. Clearly understandable and mechanistic approaches are …
completely cure cancers. Clearly understandable and mechanistic approaches are …
In vitro and in vivo evaluation of 211At-labeled fibroblast activation protein inhibitor for glioma treatment
H Ma, F Li, G Shen, L Pan, W Liu, R Liang, T Lan… - Bioorganic & Medicinal …, 2022 - Elsevier
Glioma is the most common primary intracranial tumor without effective treatment. Positron
emission tomography tracers labeled with 68 Ga targeting fibroblast activation protein (FAP) …
emission tomography tracers labeled with 68 Ga targeting fibroblast activation protein (FAP) …
Recent progress of astatine-211 in endoradiotherapy: Great advances from fundamental properties to targeted radiopharmaceuticals
F Li, Y Yang, J Liao, N Liu - Chinese Chemical Letters, 2022 - Elsevier
Abstract Astatine-211 (211 At, t 1/2= 7.21 h) emitting two α particles with energies of 5.87
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …
and 7.45 MeV, can lead to a high linear energy transfer (LET= 98.84 keV/µm) and short …
Development of a 213bi-labeled pyridyl benzofuran for targeted α-therapy of amyloid-β aggregates
AA Bender, EK Kirkeby, DJ Cross… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
Alzheimer disease is a neurodegenerative disorder with limited treatment options. It is
characterized by the presence of several biomarkers, including amyloid-β aggregates, which …
characterized by the presence of several biomarkers, including amyloid-β aggregates, which …
The current status and future directions on nanoparticles for tumor molecular imaging
C Yin, P Hu, L Qin, Z Wang, H Zhao - International Journal of …, 2024 - Taylor & Francis
Molecular imaging is an advanced technology that utilizes specific probes or markers in
conjunction with cutting-edge imaging techniques to observe and analyze the localization …
conjunction with cutting-edge imaging techniques to observe and analyze the localization …
Theranostic nanoparticles for detection and treatment of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most recalcitrant cancers due to its
late diagnosis, poor therapeutic response, and highly heterogeneous microenvironment …
late diagnosis, poor therapeutic response, and highly heterogeneous microenvironment …
Radioimmunoconjugates in the age of modern immuno-oncology
Immunotherapy was first investigated as a therapeutic option for treating cancer more than a
century ago. During this period, it has gone through numerous disappointments when the …
century ago. During this period, it has gone through numerous disappointments when the …