Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Risk factors associated with post− COVID-19 condition: a systematic review and meta-analysis

V Tsampasian, H Elghazaly… - JAMA internal …, 2023 - jamanetwork.com
Importance Post− COVID-19 condition (PCC) is a complex heterogeneous disorder that has
affected the lives of millions of people globally. Identification of potential risk factors to better …

[HTML][HTML] Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

M Taquet, R Sillett, L Zhu, J Mendel… - The Lancet …, 2022 - thelancet.com
Background COVID-19 is associated with increased risks of neurological and psychiatric
sequelae in the weeks and months thereafter. How long these risks remain, whether they …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

The immunology and immunopathology of COVID-19

M Merad, CA Blish, F Sallusto, A Iwasaki - Science, 2022 - science.org
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …

Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children

D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi… - Science, 2022 - science.org
Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that
follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or …

The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses

SM Murray, AM Ansari, J Frater, P Klenerman… - Nature Reviews …, 2023 - nature.com
Pre-existing cross-reactive immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …

Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …