Comparison of biochemical effects of statins and fish oil in brain: the battle of the titans
AA Farooqui, WY Ong, LA Horrocks, P Chen… - Brain research …, 2007 - Elsevier
Neural membranes are composed of glycerophospholipids, sphingolipids, cholesterol and
proteins. The distribution of these lipids within the neural membrane is not random but …
proteins. The distribution of these lipids within the neural membrane is not random but …
Lipid mediators in the nucleus: Their potential contribution to Alzheimer's disease
AA Farooqui, WY Ong, T Farooqui - … Acta (BBA)-Molecular and Cell Biology …, 2010 - Elsevier
Degradation of glycerophospholipids, sphingolipids and cholesterol in the nucleus
modulates neural cell proliferation and differentiation, inflammation, apoptosis, migration …
modulates neural cell proliferation and differentiation, inflammation, apoptosis, migration …
The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes
R Lappano, AG Recchia, EM De Francesco… - PloS one, 2011 - journals.plos.org
Background The hydroxylated derivatives of cholesterol, such as the oxysterols, play
important roles in lipid metabolism. In particular, 25-hydroxycholesterol (25HC) has been …
important roles in lipid metabolism. In particular, 25-hydroxycholesterol (25HC) has been …
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway
S Wang, Y Yao, C Rao… - … journal of oncology, 2019 - spandidos-publications.com
Hyperlipidemia is associated with metastasis in patients with gastric cancer (GC). 25‑
Hydroxycholesterol (25‑HC) is a type of oxysterol which is synthesized from cholesterol and …
Hydroxycholesterol (25‑HC) is a type of oxysterol which is synthesized from cholesterol and …
Oxysterol binding protein-related protein 8 mediates the cytotoxicity of 25-hydroxycholesterol [S]
J Li, X Zheng, N Lou, W Zhong, D Yan - Journal of lipid research, 2016 - ASBMB
Oxysterols are 27-carbon oxidized derivatives of cholesterol or by-products of cholesterol
biosynthesis that can induce cell apoptosis in addition to a number of other bioactions …
biosynthesis that can induce cell apoptosis in addition to a number of other bioactions …
Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers
Oxysterols, resulting from the oxidation of cholesterol, are formed either by autoxidation,
enzymatically, or by both processes. These molecules, which are provided in more or less …
enzymatically, or by both processes. These molecules, which are provided in more or less …
OSBP-related protein 8 (ORP8) interacts with Homo sapiens sperm associated antigen 5 (SPAG5) and mediates oxysterol interference of HepG2 cell cycle
We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum/nuclear
envelope oxysterol-binding protein implicated in cellular lipid homeostasis, migration, and …
envelope oxysterol-binding protein implicated in cellular lipid homeostasis, migration, and …
Synergistic effect of glucagon-like peptide 2 (GLP-2) and of key growth factors on the proliferation of cultured rat astrocytes. Evidence for reciprocal upregulation of the …
E Velázquez, E Blázquez, JM Ruiz-Albusac - Molecular neurobiology, 2009 - Springer
The aim of this work was to determine whether the stimulating effect of glucagon-like peptide
(GLP)-2 on astrocyte proliferation could be reinforced by proliferating substances, including …
(GLP)-2 on astrocyte proliferation could be reinforced by proliferating substances, including …
Sex dimorphism in an animal model of multiple sclerosis: Focus on pregnenolone synthesis
S Giatti, R Rigolio, S Diviccaro, E Falvo… - The Journal of Steroid …, 2020 - Elsevier
Neuroactive steroids, molecules produced from cholesterol in steroidogenic cells (ie,
peripheral glands and nervous system) are physiological modulators and protective agents …
peripheral glands and nervous system) are physiological modulators and protective agents …
Glucose and several mitogenic agents modulate the glucagon-like peptide-2 receptor expression in cultured rat astrocytes
E Velázquez, Y Le Baut Ayuso… - Journal of …, 2022 - content.iospress.com
Background: Glucagon-like peptide-2 (GLP-2) is an intestinal trophic factor that induces
astrocyte proliferation through its own receptor (GLP-2R), but the control of its expression is …
astrocyte proliferation through its own receptor (GLP-2R), but the control of its expression is …