Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …

Bacteriophages (phages) are often described as obligate predators of their bacterial hosts,
and phage predation is one of the leading forces controlling the density and distribution of …

Horizontal gene transfer is an important evolutionary force, facilitating bacterial diversity. It is
thought to be pervasive in host-associated microbiomes, where bacterial densities are high …

With the overuse of antibiotics, antibiotic resistance gene (ARG) prevalence is gradually
increasing. ARGs are considered emerging contaminants that are broadly concentrated and …

There is renewed interest in bacterial viruses (phages) as alternatives to antibiotics. All
phage treatments to date have used virulent phages rather than temperate ones, as these …

Compared to bacteria of the gut microbiota, bacteriophages are still poorly characterised,
and their physiological importance is far less known. Temperate phages are probably a …

Abstract Background Inflammatory bowel diseases (IBDs) including Crohn's disease (CD)
and ulcerative colitis (UC) are characterized by chronic and debilitating gut inflammation …