The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Dysregulation of pre-mRNA splicing is a common hallmark of cancer cells and it is
associated with altered expression, localization, and mutations of the components of the …

Ferroptosis, a novel regulated cell death induced by iron-dependent lipid peroxidation, plays
an important role in tumor development and drug resistance. Long noncoding RNAs …

Ferroptosis is an iron-dependent oxidative, nonapoptotic form of regulated cell death caused
by the destruction of redox homeostasis. Recent studies have uncovered complex cellular …

DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …

With the development of sequencing technology, a large number of long non-coding RNAs
(lncRNAs) have been identified in addition to coding genes. LncRNAs, originally considered …

Long noncoding RNAs (lncRNAs) are an increasing focus of investigation due to their
implications in diverse biological processes and disease. Nevertheless, the majority of …

Background Pyroptosis is a pro-inflammatory cell death characterized by the formation of
inflammasomes. Abnormal inflammation in brain microvascular endothelial cells (BMECs) …

Antisense RNAs (asRNAs) represent an underappreciated yet crucial layer of gene
expression regulation. Generally thought to modulate their sense genes in cis through …

Sin3 is an evolutionarily conserved repressor protein complex mainly associated with
histone deacetylase (HDAC) activity. Many proteins are part of Sin3/HDAC complexes, and …