Recent advances bioactive 1, 2, 4-triazole-3-thiones
ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …
atoms and three nitrogen atoms. These structures have been interest in the development of …
A review on 'triazoles': Their chemistry, synthesis and pharmacological potentials
Heterocyclic compounds are cyclic compounds as an atom of ring members with at least two
different elements. In the five-membered aromatic azole chain, triazole compounds …
different elements. In the five-membered aromatic azole chain, triazole compounds …
Chemistry and biological activities of 1, 2, 4-triazolethiones—antiviral and anti-infective drugs
Mercapto-substituted 1, 2, 4-triazoles are very interesting compounds as they play an
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …
In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2, 4‐dihydro‐3H‐1, 2, 4‐triazole‐3‐thiones—Evaluation of their …
Abstract The 1, 2, 4‐triazole and its derivatives were reported to exhibit various
pharmacological activities such as antimicrobial, analgesic, anti‐inflammatory, antitumoural …
pharmacological activities such as antimicrobial, analgesic, anti‐inflammatory, antitumoural …
Molecular science for drug development and biomedicine
WZ Zhong, SF Zhou - International journal of molecular sciences, 2014 - mdpi.com
With the avalanche of biological sequences generated in the postgenomic age, molecular
science is facing an unprecedented challenge, ie, how to timely utilize the huge amount of …
science is facing an unprecedented challenge, ie, how to timely utilize the huge amount of …
[HTML][HTML] Thiazole, triazole, thio-and semicarbazone derivatives-Promising moieties for drug development for the treatment of tuberculosis
Thiazole, triazole, thio and semicarbazones are privileged motifs that act as
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …
Synthesis, characterization, linear and NLO properties of novel N-(2, 4-dinitrobenzylidene)-3-chlorobenzenamine schiff base: combined experimental and DFT …
This study entails two parts: The first reports on the synthesis of a novel N-(2, 4-
dinitrobenzylidene)-3-chlorobenzenamine Schiff base and its analysis by ultraviolet–visible …
dinitrobenzylidene)-3-chlorobenzenamine Schiff base and its analysis by ultraviolet–visible …
Tautomerism and structure of azoles: nuclear magnetic resonance spectroscopy
LI Larina - Advances in heterocyclic chemistry, 2018 - Elsevier
This review provides comprehensive data (from the author's work and the literature) on
tautomerism of pyrazoles, imidazoles, 1, 2, 3-and 1, 2, 4-triazoles, tetrazoles …
tautomerism of pyrazoles, imidazoles, 1, 2, 3-and 1, 2, 4-triazoles, tetrazoles …
Facile synthesis, pharmacological and In silico analysis of succinimide derivatives: An approach towards drug discovery
J Rasgania, R Gavadia, K Jakhar - Journal of Molecular Structure, 2023 - Elsevier
The hybrid heterocyclic scaffolds possess extensive medicinal values and significant
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …
Synthesis, biological evaluation and molecular dynamics studies of 1, 2, 4-triazole clubbed Mannich bases
The present work highlightsthe synthesis of a newer biologically active Mannich bases
contributing 4-((4-fluorobenzylidene) amino)-5-(pyridin-4-yl)-4H-1, 2, 4-triazole-3-thiol and …
contributing 4-((4-fluorobenzylidene) amino)-5-(pyridin-4-yl)-4H-1, 2, 4-triazole-3-thiol and …