Moxidectin: an oral treatment for human onchocerciasis

P Milton, JID Hamley, M Walker… - Expert Review of anti …, 2020 - Taylor & Francis
Introduction Moxidectin is a milbemycin endectocide recently approved for the treatment of
human onchocerciasis. Onchocerciasis, earmarked for elimination of transmission, is a …

Community-directed distributors—The “foot soldiers” in the fight to control and eliminate neglected tropical diseases

UV Amazigo, SGA Leak, HGM Zoure… - PLoS neglected …, 2021 - journals.plos.org
The neglected tropical diseases (NTDs) affect hundreds of millions of people, predominantly
in rural, often difficult-to-access areas, poorly served by national health services. Here, we …

[HTML][HTML] Epidemiology of epilepsy and relationship with onchocerciasis prevalence in villages of the Ntui Health District of Cameroon

L Ngarka, JNS Fodjo, C Ambomatei, WY Njamnshi… - Epilepsy & Behavior, 2023 - Elsevier
Background A strong association between epilepsy and onchocerciasis endemicity has
been reported. We sought to document the epidemiology of epilepsy in onchocerciasis …

Individual longitudinal compliance to neglected tropical disease mass drug administration programmes, a systematic review

R Maddren, A Phillips, S Rayment Gomez… - PLOS Neglected …, 2023 - journals.plos.org
Repeated distribution of preventative chemotherapy (PC) by mass drug administration forms
the mainstay of transmission control for five of the 20 recognised neglected tropical diseases …

Non-adherence to ivermectin in onchocerciasis-endemic communities with persistent infection in the Bono Region of Ghana: a mixed-methods study

KB Otabil, MG Basáñez, B Ankrah… - BMC Infectious …, 2023 - Springer
Abstract Background The World Health Organization has proposed that onchocerciasis
elimination (interruption) of transmission be verified in 12 (approximately a third) endemic …

Impact of 19 years of mass drug administration with ivermectin on epilepsy burden in a hyperendemic onchocerciasis area in Cameroon

C Boullé, AK Njamnshi, F Dema, MK Mengnjo… - Parasites & …, 2019 - Springer
Background Surveys conducted in 1991–1992 in the Mbam Valley (Cameroon) revealed
that onchocerciasis was highly endemic, with community microfilarial loads (CMFL)> 100 …

Integrated people-centered eye care: A sco** review on engaging communities in eye care in low-and middle-income settings

L Lee, E Moo, T Angelopoulos, A Yashadhana - PLoS One, 2023 - journals.plos.org
Background Community engagement has been endorsed as a key strategy to achieving
integrated people-centered eye care that enables people and communities to receive a full …

Why onchocerciasis transmission persists after 15 annual ivermectin mass drug administrations in South-West Cameroon

A Forrer, S Wanji, ED Obie, TM Nji, L Hamill… - BMJ global …, 2021 - gh.bmj.com
Introduction Onchocerciasis is targeted for elimination mainly with annual community-
directed treatment with ivermectin (CDTI). High infection levels have been reported in South …

From informed consent to adherence: factors influencing involvement in mass drug administration with ivermectin for malaria elimination in The Gambia

A Fehr, C Nieto-Sanchez, J Muela, F Jaiteh, O Ceesay… - Malaria Journal, 2021 - Springer
Abstract Background The World Health Organization (WHO) recommends consideration of
mass drug administration (MDA) for malaria control in low-endemic settings approaching …

Contextual determinants of mass drug administration performance: Modelling fourteen years of lymphatic filariasis treatments in West Africa

BB Fuller, V Harris, C Parker, A Martinez… - PLOS Neglected …, 2023 - journals.plos.org
Background Effective mass drug administration (MDA) is the cornerstone in the elimination
of lymphatic filariasis (LF) and a critical component in combatting all neglected tropical …