Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …

Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

The immune response to acute cerebral ischemia is a major factor in stroke pathobiology
and outcome. While the immune response starts locally in occluded and hypoperfused …

Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

Acute brain ischemia induces a local neuroinflammatory reaction and alters peripheral
immune homeostasis at the same time. Recent evidence has suggested a key role of the gut …

Toll-like receptors (TLRs) are discovered as crucial pattern recognition receptors (PRRs)
involved in the recognition of pathogen-associated molecular patterns (PAMPs). Later …

Background Inflammatory response has been recognized as a pivotal pathophysiological
process during cerebral ischemic stroke. NLRP3 inflammasome, involved in the regulation …

Ischemic stroke prompts a strong inflammatory response, which is associated with
exacerbated outcomes. In this study, we investigated mechanistic regulators of neutrophil …

There is increasing evidence of the influence of the gut microbiota on hypertension and its
complications, such as chronic kidney disease, stroke, heart failure, and myocardial …

Cerebral stroke is ranked as the third most common contributor to global mortality and
disability. The involvement of inflammatory mechanisms, both peripherally and within the …