[HTML][HTML] Mammalian mitochondria and aging: an update
TES Kauppila, JHK Kauppila, NG Larsson - Cell metabolism, 2017 - cell.com
Mitochondria were first postulated to contribute to aging more than 40 years ago. During the
following decades, multiple lines of evidence in model organisms and humans showed that …
following decades, multiple lines of evidence in model organisms and humans showed that …
Horizons in the evolution of aging
T Flatt, L Partridge - BMC biology, 2018 - Springer
Between the 1930s and 50s, evolutionary biologists developed a successful theory of why
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
Lifetime reproductive success of northern elephant seals (Mirounga angustirostris)
Lifetime reproductive success of individuals in a natural population provides an estimate of
Darwinian fitness. We calculated lifetime reproductive success in a colony of female …
Darwinian fitness. We calculated lifetime reproductive success in a colony of female …
Early-late life trade-offs and the evolution of ageing in the wild
Empirical evidence for declines in fitness components (survival and reproductive
performance) with age has recently accumulated in wild populations, highlighting that the …
performance) with age has recently accumulated in wild populations, highlighting that the …
Evolution of ageing as a tangle of trade-offs: energy versus function
Despite tremendous progress in recent years, our understanding of the evolution of ageing
is still incomplete. A dominant paradigm maintains that ageing evolves due to the competing …
is still incomplete. A dominant paradigm maintains that ageing evolves due to the competing …
Oxidative stress and hormesis in evolutionary ecology and physiology
D Costantini - A marriage between mechanistic and evolutionary …, 2014 - Springer
Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …
toxicological sciences have traditionally centralised such research, but in the last years we …
Slow and negligible senescence among testudines challenges evolutionary theories of senescence
Is senescence inevitable and universal for all living organisms, as evolutionary theories
predict? Although evidence generally supports this hypothesis, it has been proposed that …
predict? Although evidence generally supports this hypothesis, it has been proposed that …
Causes and consequences of individual variability and specialization in foraging and migration strategies of seabirds
Technological advances in recent years have seen an explosion of tracking and stable
isotope studies of seabirds, often involving repeated measures from the same individuals …
isotope studies of seabirds, often involving repeated measures from the same individuals …
Reproductive senescence: new perspectives in the wild
According to recent empirical studies, reproductive senescence, the decline in reproductive
success with increasing age, seems to be nearly ubiquitous in the wild. However, a clear …
success with increasing age, seems to be nearly ubiquitous in the wild. However, a clear …
Is antagonistic pleiotropy ubiquitous in aging biology?
Abstract Lay Summary: An evolutionary mechanism of aging was hypothesized 60 years
ago to be the genetic trade-off between early life fitness and late life mortality. Genetic …
ago to be the genetic trade-off between early life fitness and late life mortality. Genetic …