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Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …
Deficits in behavioural inhibition in substance abuse and addiction: a meta-analysis
Aims Deficits in behavioural inhibitory control are attracting increasing attention as a factor
behind the development and maintenance of substance dependence. However, evidence …
behind the development and maintenance of substance dependence. However, evidence …
Dopamine and glucose, obesity, and reward deficiency syndrome
Obesity as a result of overeating as well as a number of well described eating disorders has
been accurately considered to be a world-wide epidemic. Recently a number of theories …
been accurately considered to be a world-wide epidemic. Recently a number of theories …
Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity
Moves to legalize marijuana highlight the urgency to investigate effects of chronic marijuana
in the human brain. Here, we challenged 48 participants (24 controls and 24 marijuana …
in the human brain. Here, we challenged 48 participants (24 controls and 24 marijuana …
[HTML][HTML] Predicting the transition from frequent cannabis use to cannabis dependence: a three-year prospective study
Background Frequent cannabis users are at high risk of dependence, still most (near) daily
users are not dependent. It is unknown why some frequent users develop dependence …
users are not dependent. It is unknown why some frequent users develop dependence …
Age and impulsive behavior in drug addiction: A review of past research and future directions
Impulsive behavior is implicated in the initiation, maintenance, and relapse of drug-seeking
behaviors involved in drug addiction. Research shows that changes in impulsive behavior …
behaviors involved in drug addiction. Research shows that changes in impulsive behavior …
High times for cannabis: Epigenetic imprint and its legacy on brain and behavior
Extensive debates continue regarding marijuana (Cannabis spp), the most commonly used
illicit substance in many countries worldwide. There has been an exponential increase of …
illicit substance in many countries worldwide. There has been an exponential increase of …
Trajectory of adolescent cannabis use on addiction vulnerability
The adolescent brain is a period of dynamic development making it vulnerable to
environmental factors such as drug exposure. Of the illicit drugs, cannabis is most used by …
environmental factors such as drug exposure. Of the illicit drugs, cannabis is most used by …
Early intervention following trauma may mitigate genetic risk for PTSD in civilians: a pilot prospective emergency department study
Background: Civilian posttraumatic stress disorder (PTSD) and combat PTSD are major
public health concerns. Although a number of psychosocial risk factors have been identified …
public health concerns. Although a number of psychosocial risk factors have been identified …
Sha** vulnerability to addiction–the contribution of behavior, neural circuits and molecular mechanisms
Substance use disorders continue to impose increasing medical, financial and emotional
burdens on society in the form of morbidity and overdose, family disintegration, loss of …
burdens on society in the form of morbidity and overdose, family disintegration, loss of …