Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications

LA Milton, MS Viglione, LJY Ong, GP Nordin, YC Toh - Lab on a Chip, 2023 - pubs.rsc.org
Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …

Human organoids-on-chips for biomedical research and applications

H Wang, X Ning, F Zhao, H Zhao, D Li - Theranostics, 2024 - pmc.ncbi.nlm.nih.gov
Human organoids-on-chips (OrgOCs) are the synergism of human organoids (HOs)
technology and microfluidic organs-on-chips (OOCs). OOCs can mimic extrinsic …

Immunotherapy discovery on tumor organoid-on-a-chip platforms that recapitulate the tumor microenvironment

J Zhang, H Tavakoli, L Ma, X Li, L Han, XJ Li - Advanced drug delivery …, 2022 - Elsevier
Cancer immunotherapy has achieved remarkable success over the past decade by
modulating patients' own immune systems and unleashing pre-existing immunity. However …

[HTML][HTML] Recent advances of organ-on-a-chip in cancer modeling research

X Liu, Q Su, X Zhang, W Yang, J Ning, K Jia, J **n, H Li… - Biosensors, 2022 - mdpi.com
Although many studies have focused on oncology and therapeutics in cancer, cancer
remains one of the leading causes of death worldwide. Due to the unclear molecular …

Flourishing tumor organoids: History, emerging technology, and application

Q Yang, M Li, X Yang, Z **ao, X Tong… - Bioengineering & …, 2023 - Wiley Online Library
Malignant tumors are one of the leading causes of death which impose an increasingly
heavy burden on all countries. Therefore, the establishment of research models that closely …

[HTML][HTML] Diagnosis methods for COVID-19: a systematic review

R Maia, V Carvalho, B Faria, I Miranda, S Catarino… - Micromachines, 2022 - mdpi.com
At the end of 2019, the coronavirus appeared and spread extremely rapidly, causing millions
of infections and deaths worldwide, and becoming a global pandemic. For this reason, it …

[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …

[HTML][HTML] Emerging microfluidics for the modeling and treatment of arthritis

N Yang, C Sun, C Dong, Y Huang, Y Zhu, Z Gu - Engineered Regeneration, 2024 - Elsevier
Microfluidic is a technology that allows the precise control of fluid in a micro-channel. With its
advantages of high throughput and low cost, microfluidic technology has achieved good …

Recent advances in Organ-on-a-Chip models: How precision engineering integrates cutting edge technologies in fabrication and characterization

S Sadeghzade, MH Hooshiar, H Akbari… - Applied Materials …, 2024 - Elsevier
There is an increasing need for better preclinical therapeutic development models suitable
for the human body. As a result, there has been a shift from traditional animal models to …

[HTML][HTML] On-chip recapitulation of the tumor microenvironment: A decade of progress

SM Giannitelli, V Peluzzi, S Raniolo, G Roscilli… - Biomaterials, 2024 - Elsevier
One of the hurdles to the development of new anticancer therapies is the lack of in vitro
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …