Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

Abstract The UCSC Genome Browser (https://genome. ucsc. edu) is a web-based genomic
visualization and analysis tool that serves data to over 7,000 distinct users per day …

Thousands of genomic regions have been associated with heritable human diseases, but
attempts to elucidate biological mechanisms are impeded by an inability to discern which …

Within the next decade, the genomes of 1.8 million eukaryotic species will be sequenced.
Identifying genes in these sequences is essential to understand the biology of the species …

The era of biodiversity genomics is characterized by large-scale genome sequencing efforts
that aim to represent each living taxon with an assembled genome. Generating knowledge …

The planarian Schmidtea mediterranea is being studied as a model species for
regeneration, but the assembly of planarian genomes remains challenging. Here, we report …

Zoonoses are infectious diseases transmitted from animals to humans. Bats have been
suggested to harbour more zoonotic viruses than any other mammalian order. Infections in …

Analyses of ancient DNA typically involve sequencing the surviving short oligonucleotides
and aligning to genome assemblies from related, modern species. Here, we report that skin …

We present haplotype-resolved reference genomes and comparative analyses of six ape
species, namely: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan …

Cell types with specialized functions fundamentally regulate animal behaviour, and yet the
genetic mechanisms that underlie the emergence of novel cell types and their …