Applications of single-cell sequencing in cancer research: progress and perspectives
Y Lei, R Tang, J Xu, W Wang, B Zhang, J Liu… - Journal of hematology & …, 2021 - Springer
Single-cell sequencing, including genomics, transcriptomics, epigenomics, proteomics and
metabolomics sequencing, is a powerful tool to decipher the cellular and molecular …
metabolomics sequencing, is a powerful tool to decipher the cellular and molecular …
[HTML][HTML] New insights from the single-cell level: tumor associated macrophages heterogeneity and personalized therapy
X Wang, Y Xu, Q Sun, X Zhou, W Ma, JB Wu… - Biomedicine & …, 2022 - Elsevier
Tumor-associated macrophages (TAMs) are important immune cells in the tumor
microenvironment, and their invasion in tumors is closely related to poor prognosis …
microenvironment, and their invasion in tumors is closely related to poor prognosis …
B2M overexpression correlates with malignancy and immune signatures in human gliomas
Because of the limited treatment strategy of gliomas, the key of diagnosis and treatment is
finding new molecular biomarkers. Here, we explored the potential of β2-microglobulin …
finding new molecular biomarkers. Here, we explored the potential of β2-microglobulin …
Immune infiltrating cells-derived risk signature based on large-scale analysis defines immune landscape and predicts immunotherapy responses in glioma tumor …
The glioma tumor microenvironment (TME), composed of several noncancerous cells and
biomolecules is known for its complexity of cancer-immune system interaction. Given that …
biomolecules is known for its complexity of cancer-immune system interaction. Given that …
Protein disulfide-isomerase A3 is a robust prognostic biomarker for cancers and predicts the immunotherapy response effectively
Z Tu, Q Ouyang, X Long, L Wu, J Li, X Zhu… - Frontiers in …, 2022 - frontiersin.org
Background Protein disulfide isomerase A3 (PDIA3) is a member of the protein disulfide
isomerase (PDI) family that participates in protein folding through its protein disulfide …
isomerase (PDI) family that participates in protein folding through its protein disulfide …
Characterization of an endoplasmic reticulum stress‐related signature to evaluate immune features and predict prognosis in glioma
Q Zhang, G Guan, P Cheng, W Cheng… - Journal of cellular …, 2021 - Wiley Online Library
Endoplasmic reticulum (ER) stress has considerable impact on cell growth, proliferation,
metastasis, invasion, angiogenesis and chemoradiotherapy resistance in various cancers …
metastasis, invasion, angiogenesis and chemoradiotherapy resistance in various cancers …
Novel immune infiltrating cell signature based on cell pair algorithm is a prognostic marker in cancer
Tumor-infiltrating immune cells (TIICs) have become an important source of markers for
predicting the clinical outcomes of cancer patients. However, measurements of cellular …
predicting the clinical outcomes of cancer patients. However, measurements of cellular …
The predictive value of monocytes in immune microenvironment and prognosis of glioma patients based on machine learning
N Zhang, Z Dai, W Wu, Z Wang, H Cao… - Frontiers in …, 2021 - frontiersin.org
Gliomas are primary malignant brain tumors. Monocytes have been proved to actively
participate in tumor growth. Weighted gene co-expression network analysis was used to …
participate in tumor growth. Weighted gene co-expression network analysis was used to …
Ferroptosis‐Related Gene Signature Promotes Ovarian Cancer by Influencing Immune Infiltration and Invasion
Y You, Q Fan, J Huang, Y Wu, H Lin… - Journal of …, 2021 - Wiley Online Library
Ovarian cancer is a kind of gynecological malignancy with high mortality. Ferroptosis is a
new type of iron‐dependent cell death characterized by the formation of lipid peroxides and …
new type of iron‐dependent cell death characterized by the formation of lipid peroxides and …
[HTML][HTML] PDIA3 modulates genomic response to 1, 25-dihydroxyvitamin D3 in squamous cell carcinoma of the skin
JI Nowak, AM Olszewska, A Piotrowska, K Myszczyński… - Steroids, 2023 - Elsevier
An active form of vitamin D 3 (1, 25-dihydroxyvitamin D 3) acts through vitamin D receptor
(VDR) initiating genomic response, but several studies described also non-genomic actions …
(VDR) initiating genomic response, but several studies described also non-genomic actions …